Mayo Clinic's approach

Mayo Clinic doctors are skilled at using cryotherapy and other ablation procedures to treat prostate cancer. People with prostate cancer often have many treatment options to consider. At Mayo Clinic, caring doctors take the time to explain your options, help you weigh the benefits and risks of treatments, and support you in making decisions about your care.

Your Mayo Clinic care team

The doctors at Mayo Clinic Comprehensive Cancer Center provide excellent care for people with prostate cancer. Mayo Clinic Comprehensive Cancer Center is the only National Cancer Institute-designated comprehensive cancer center with three locations, in Arizona, Florida and Minnesota.

At Mayo Clinic, doctors and other specialists work in multidisciplinary teams to address all of your needs and explore all of your options. Benefits of the team approach include:

  • Expertise across all disciplines. Mayo Clinic doctors are highly skilled not in some aspects of prostate cancer care but across all specialties involved in care for people with the condition.
  • Collaboration. Mayo Clinic urologists, oncologists, radiation oncologists, pathologists and radiologists rely on strong collaboration and multidisciplinary discussion to provide comprehensive care to each person with prostate cancer.

Advanced diagnosis and treatment

Mayo Clinic doctors have access to the latest diagnosis and treatment innovations to provide you with an accurate diagnosis and effective treatment plan. This includes:

  • The latest imaging tests for treatment planning. Mayo Clinic doctors use the latest imaging techniques to plan your cryotherapy treatment. Multiparametric MRI (mpMRI), ultrasound and other imaging tests show the size and location of the cancer so doctors can carefully design a treatment plan that increases treatment effectiveness.
  • Modern cryotherapy equipment. Mayo Clinic doctors use modern cryotherapy equipment that gives them precise control during the procedure. Doctors carefully shape the treatment area so that the freezing targets tissue in the prostate while minimizing effects on the surrounding tissue.

Expertise and rankings

Mayo Clinic doctors are widely respected for their experience and expertise in caring for people with prostate cancer. When you seek care at Mayo Clinic, you can expect:

  • Personalized care. Mayo Clinic urologists, oncologists, radiation oncologists, pathologists and radiologists work together to ensure all of your needs are addressed when creating your customized treatment plan.
  • A full range of treatment options. Mayo Clinic offers all of the available treatment options for prostate cancer. Your care team determines which treatments are most effective in your specific situation and works closely with you to choose the treatments that meet your needs and preferences.
  • Experience you can trust. Each year, more than 23,000 people with prostate cancer receive care at Mayo Clinic. This experience means your care team is prepared with the knowledge and resources to provide you with exactly the care you need.
  • Nationally recognized expertise. Mayo Clinic Comprehensive Cancer Center meets the strict standards for a National Cancer Institute-designated comprehensive cancer center. These standards recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic in Rochester, Minnesota, is ranked as the top hospital in Minnesota and Mayo Clinic in Phoenix/Scottsdale, Arizona, is ranked as the top hospital in Arizona.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

March 04, 2026
  1. Smith JA, et al., eds. Prostate cancer cryosurgery. In: Hinman's Atlas of Urologic Surgery. 5th ed. Elsevier; 2026. https://www.clinicalkey.com. Accessed Jan. 9, 2026.
  2. Pisters LL, et al. Cryotherapy and other ablative techniques for the initial treatment of prostate cancer. https://www.uptodate.com/contents/search. Accessed Jan. 9, 2026.
  3. Prostate cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=2&id=1459. Accessed Jan. 9, 2026.
  4. Richie JP. Rising serum PSA after radiation therapy for localized prostate cancer: Salvage local therapy. https://www.uptodate.com/contents/search. Accessed Jan. 9, 2026.
  5. Cryotherapy, HIFU and other ablative treatments for prostate cancer. American Cancer Society. https://www.cancer.org/cancer/types/prostate-cancer/treating/cryosurgery.html. Accessed Jan. 9, 2026.
  6. Harris KM. Allscripts EPSi. Mayo Clinic. April 23, 2024.

Cryotherapy for prostate cancer