A high uric acid level, or hyperuricemia, is an excess of uric acid in your blood. Uric acid is produced during the breakdown of purines, which are found in certain foods and are also formed by your body.
Once produced, uric acid is carried in your blood and passes through your kidneys, where most of it is filtered out into the urine.
About one in five people has a high uric acid level. It may be related to attacks of gout or the development of kidney stones. But most people with high uric acid levels don't have any symptoms or related problems.
Nov. 24, 2020
Get the latest health information from Mayo Clinic’s experts.
Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health.
ErrorEmail field is required
ErrorInclude a valid email address
To provide you with the most relevant and helpful information, and understand which
information is beneficial, we may combine your email and website usage information with
other information we have about you. If you are a Mayo Clinic patient, this could
include protected health information. If we combine this information with your protected
health information, we will treat all of that information as protected health
information and will only use or disclose that information as set forth in our notice of
privacy practices. You may opt-out of email communications at any time by clicking on
the unsubscribe link in the e-mail.
Thank you for subscribing
Our Housecall e-newsletter will keep you up-to-date on the latest health information.
Sorry something went wrong with your subscription
Please, try again in a couple of minutes
- Uric acid. Lab Tests Online. http://labtestsonline.org/understanding/analytes/uric-acid/tab/glance. Accessed Oct. 6, 2015.
- Questions and answers about gout. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/Health_Info/Gout/default.asp. Accessed Oct. 6, 2015.
- Kim SY, et al. Hyperuricemia and coronary heart disease: A systematic review and meta-analysis. Arthritis Care & Research. 2010;62:170.
- Ohno, I. Relationship between hyperuricemia and chronic kidney disease. Nucleosides, Nucleotides and Nucleic Acids. 2011;30:1039.
- Kanbay M, et al. Uric acid in hypertension and renal disease: The chicken or the egg? Blood Purification. 2010;30:288.
- Hochberg J, et al. Tumor lysis syndrome: Current perspective. Haematologica. 2008;93:9.
- So A, et al. Uric acid transport and disease. The Journal of Clinical Investigation. 2010;120:1791.
- Becker MA. Asymptomatic hyperuricemia. http://www.uptodate.com/home. Accessed Nov. 2, 2015.
- Wilkinson JM (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 29, 2015.