Search Results 1-10 of 17107 for autophagy activation

  1. A Study to Evaluate AuTophagy Activation for Cardiomyopathy Due to Anthracycline tReatment - Mayo Clinic

    The purpose of this study is to evaluate the additional benefit of pravastatin and spironolactone when given in combination with carvedilol and lisinopril ...

  2. Disease Relevance of Mitophagy - Translational Cell Biology of Parkinson's Disease Laboratory - Mayo Clinic Research

    ... activation of the pathway and follow its flux through the autophagic-lysosomal system in cell lines, neurons and tissues. Using emerging, detailed ...

  3. Neural control of the diaphragm muscle - Cell and Regenerative Physiology Laboratory - Mayo Clinic Research

    Sieck's research team is determining whether phrenic motor neuron loss is due to altered mitochondrial function or changes in motor neuron autophagy, mitophagy ...

  4. Zebrafish PKD-Targeted Services - Model Systems Core - Mayo Clinic Research

    Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model. Human Molecular Genetics. 2017; doi:10.1093/hmg/ddw376 ...

  5. Cell and Molecular Aging Laboratory - Mayo Clinic Research

    ... autophagy, promote TAF formation. Based on extensive experimental evidence ... activation of the SASP. More recently, the group showed that ...

  6. Immune Cell Activation of Healthy Human Subjects - Mayo Clinic

    The studies in our laboratory investigate the role of human blood cells in immunity to fungal disease and lung fibrosis. Most of our studies require blood that ...

  7. Gary C. Sieck, Ph.D. - Mayo Clinic Faculty Profiles

    ... autophagy and mitophagy. Dr. Sieck hypothesizes ... Sieck explores the activation of muscle ... Activation of this ER stress pathway results in a ...

  8. Understanding the molecular mechanisms that affect motor unit and muscle health during aging - Mayo Clinic

    Are there other processes that could potentially mediate the effects of aging on muscle? Autophagy is a cellular process that aids in protein degradation and ...

  9. A Study to Analyze Isolation, Activation and Expansion of Mutation Reactive T-cells - Mayo Clinic

    Circulating cell-free DNA (cfDNA) from the plasma will be extracted and sequenced to identify somatic mutations that were exposed to the T-cells. Participation ...

  10. Cardiomyopathy Clinical Trials - Mayo Clinic Research

    A Study to Evaluate AuTophagy Activation for Cardiomyopathy Due to Anthracycline tReatment Rochester, MN. The purpose of this study is to evaluate the ...