Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
Search Results 1-10 of 16 for Somatic
Special emphasis is on discovery and analysis of somatic variants — those originating in human cells during their life span — as they can cause cancer and various diseases.
Additional drivers of lymphomagenesis include chromosomal copy number alterations (amplifications and deletions) and somatic mutations.
These studies contribute to an improved understanding of the mechanisms that underlie the development of physical morbidity and disability in those with somatic symptom disorders.
From a detailed analysis of the breakpoints, it is clear that the translocations are frequently mediated by aberrant activity of B cell-specific mechanisms: somatic hypermutation and isotype switch recombination.
Hickey and colleagues have pioneered the use of gene targeting and somatic cell nuclear transfer to develop large models of inborn errors of metabolism, including the first genetically engineered model of a liver disease — tyro...
Somatic mutation, copy number variation, epigenetic alteration and aberrant RNA splicing are common in human cancers.
Nowakowski is researching somatic mutations of BCL2, with the goal of selecting the appropriate therapies for specific patients.
Furthermore, iPSCs are generated using somatic cells from individual patients; they can be used for stem cell therapy with lower risks of rejection reactions.
., include the development of molecular genetic assays for the diagnosis, prognosis and treatment of solid tumors; clinical next-generation sequencing (NGS) technology for hereditary and somatic diseases; and molecular cytology and c...
Research Topic: Targeting of somatic hypermutation in B cells Department of Cell Biology, Albert Einstein College of Medicine Post Doctoral Fellowship - Mentor: Selina Chen-Kiang, PhD.
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.