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Search Results 1-10 of 11 for Ribosome
"While it's been known for a long time that tumor cells have elevated ribosome levels, this paper is the first to show that Ect2 supports tumor cell growth by stimulating ribosome biogenesis."
Huang's team uses advanced techniques that include but are not limited to: Gene knockout via clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 (CRISPR/Cas9) Gene knockout and knockin in mouse embryo stem cells Tumor imagin...
There is a long-recognized association between ribosome biogenesis and cellular transformation.
Experiments designed to decipher the underlying causes revealed that cyclin A2 harbors a unique functional unit that allows it to bind to the gene transcripts of Mre11 to usher them to ribosomes, which are particles specialized in tr...
Research goals In this collaborative study with University of Minnesota investigators, researchers in the Epidemiology and Genetics of Lung Cancer Research Program aim to: Define precise clinical disease phenotypes of COPD and lung cancer and identif...
Many advanced techniques routinely utilized in the laboratory include gene knockout by transcription activator-like effector nuclease (TALEN) and clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 (CRISPR/Cas9), tumor imagi...
Caulfield also serves as a principle investigator for studies on ribosome modeling and design of next-generation antibiotics; antimalarial compounds; anti-aging compounds modeled in "wheelhouse" organisms (rotifera); and computationa...
Experiments designed to decipher the underlying causes revealed that cyclin A2 harbors a unique functional unit that allows it to bind to Mre11 gene transcripts to usher them to ribosomes, which are particles specialized in translati...
The department has particular expertise in the development of new molecular assays for microbe identification utilizing methods, such as real-time PCR, ribosome sequencing, mass spectrometry, and in situ hybridization.
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