Quality CareFind out why Mayo Clinic is the right place for your health care. Make an appointment.
Meet the StaffFind a directory of doctors and departments at all Mayo Clinic campuses. Visit now.
Research and Clinical TrialsSee how Mayo Clinic research and clinical trials advance the science of medicine and improve patient care. Explore now.
Visit Our SchoolsEducators at Mayo Clinic train tomorrow’s leaders to deliver compassionate, high-value, safe patient care. Choose a degree.
Professional ServicesExplore Mayo Clinic's many resources and see jobs available for medical professionals. Get updates.
Philanthropy at Mayo ClinicYour support accelerates powerful innovations in patient care, research and education. Give today.
Search Results 1-8 of 8 for Proto-oncogene
Specifically, we are interested in the role of epidermal growth factor receptor (EGFR), a frequently mutated oncogene in gliomas, and its effect on the expression of effector molecules (integrins and proteinases) that drive tumor inv...
Oncogene dysregulation in lymphoma.
A current focus is on the MYC oncogene that appears in some patients to cause the progression of MGUS to myeloma.
Over-expression of MUC1 in the mouse mammary gland results in tumor formation, indicating that MUC1 is an oncogene.
In pancreatic cancer, the oncogene KRas contributes to a metabolic rewiring of tumor cells.
Discoveries from the Copland laboratory include RhoB, transforming growth factor receptor 3 (TBR3) and GATA3 as tumor suppressor genes in addition to FOXO3a, stearoyl CoA desaturase 1 (SCD1), neuronal pentraxin 2 (NPTX2) and others as novel oncogenes...
A major subtype accounting for 30 percent of lung cancer diagnoses, LSCC is characterized by poor therapeutic response, a high relapse rate, poor prognosis and a lack of actionable oncogene targets.
Galardy's laboratory demonstrated that this enzyme is in fact an oncogene that drives the development of lung tumors and B-cell cancers (lymphoma and plasma cell tumors) and is required for the ongoing survival of cancers in which it...
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.