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Search Results 1-10 of 10 for Paracrine
Researchers in the lab are interested in creating liver-on-chip devices to study paracrine signals being exchanged between liver cell compartments during injury.
This factor produced by breast cancer cells is a low molecular weight protein secreted in the media as an inhibitory paracrine factor.
Recent evidence suggests that the beneficial effects of stem cells in tissue regeneration are largely due to paracrine effects mediated by extracellular vesicles.
Serotonin is an important neurotransmitter and paracrine messenger in the gastrointestinal tract that plays a critical role in regulating gastrointestinal physiology in health and disease.
Functionally, IL-1beta has potent osteoclast activating factor activity, can increase the expression of adhesion molecules, and can induce paracrine IL-6 production.
Human mesenchymal cells have built-in mesodermal multipotency to induce cardiac regeneration by inducing paracrine signaling, differentiation into new cardiomyocytes and activation of endogenous cardiac stem cells.
Additionally, interests include investigating local "paracrine effects" in the breast that may point to specific mechanisms in the hormonal-inflammatory axis and potentially can be inhibited with medications.
When communication is permitted, the injured cellular compartment is allowed to exchange paracrine signals with uninjured cells.
Since it is increasingly apparent that stem cell benefit is likely due to a paracrine mechanism of action, rather than direct integration, acellular approaches are of increasing interest.
This type of study is being undertaken in order to better counsel individual patients and determine which of this heterogenous disease may require earlier therapy. c) Determine the autocrine and / or paracrine pathways that the CLL B...
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