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Search Results 1-10 of 11 for Anabolic
This project is continuing with the preclinical analyses of this novel anabolic approach to the treatment of osteoporosis.
Bradley and colleagues study how anabolic signaling is dampened by phosphatases, a class of molecular switches, and how this affects skeletal generation, cartilage degeneration and bone resorption.
He also identified vibration-induced bone-enhancing (vibe) genes in stem cells, as proof-of-principle for development of anabolic agents to promote bone and muscle strength.
Understanding how osteoclasts promote bone formation may lead to new therapies to suppress osteoclast resorption activity while preserving anabolic osteoclast functions.
Chandra's research team reduced radiation-induced bone damage and cellular apoptosis and improved bone formation using bone anabolic drugs, such as parathyroid hormone, neutralizing antibodies against sclerostin, and by stabilizing D...
The project is designed to evaluate the influence of chronic inflammation on skeletal muscle mitochondrial function and anabolic responses to resistance exercise.
Biological actions of TIEG/KLF10 in skeletal cells In a project funded by a National Institutes of Health grant, we have identified TIEG/KLF10 as an estrogen-regulated gene in bone cells that is essential for the normal bone anabolic...
Additional translational studies are being conducted to evaluate the therapeutic potential of dietary omega-3 consumption in people with insulin resistance; these dietary lipids exhibit anabolic effects, and studies are underway to e...
Hawse's group is currently examining the role of TGFβ inducible early gene-1 (TIEG) in mediating the anabolic effects of estrogen in this tissue as well as its role in bone maintenance and turnover.
Epigenetic Bone Anabolic Drugs ('Epibolics') for Bone Regeneration Collaborator: Amel Dudakovic, Ph.D.
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