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  1. A Phase 1b/2 Study of Onvansertib (PCM-075) in Combination with FOLFIRI and Bevacizumab for Second-Line Treatment of Metastatic Colorectal Cancer in Patients with a KRAS Mutation - Mayo Clinic

    Participants must have histologically confirmed metastatic and unresectable disease, and previously failed treatment or be intolerant to fluoropyrimidine and ...

  2. A Study to Evaluate Intravenous Iloprost in Subjects with Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of iloprost on the frequency of and relief from symptomatic digital ischemic episodes in ...

  3. Clinical trials - Oncology (Medical)

    The purpose of this study is to determine if the drug combination of acalabrutinib, durvalumab, and venetoclax will work to treat Richter's transformation, ...

  4. Lymphatic Malformation Clinical Trials - Mayo Clinic Research

    The purpose of this research is to see if a new topical (applied to the skin) formulation of sirolimus, PTX-022, is safe and effective in treating people with ...

  5. Efficacy And Safety Study Of Bb2121 In Subjects With Relapsed And Refractory Multiple Myeloma (KarMMa) - Mayo Clinic

    A leukapheresis procedure will be performed to manufacture bb2121 chimeric antigen receptor (CAR) modified T cells. Prior to bb2121 infusion subjects will ...

  6. Neurology - Clinical trials - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of deep brain stimulation (DBS) of the dentate nucleus area for improving functional ...

  7. Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma - Mayo Clinic

    LGX818 300mg QD monotherapy (denoted as LGX818 arm) or 3. vemurafenib 960mg BID (denoted as vemurafenib arm) Part 2: Patients will be randomized in a 3:1 ratio ...

  8. Robotic surgery - Doctors & Departments - Mayo Clinic

    Robotic systems can help surgeons increase precision, flexibility and control for many procedures. Learn about the advantages and availability of ...

  9. Arthritis - Doctors and departments - Mayo Clinic

    Learn about how different types of arthritis affect joints in different ways, along with how to get relief from arthritis pain.

  10. Drugs and Supplements that Start with C - Mayo Clinic

    Explore a comprehensive list of prescription and over-the-counter medications starting with the letter “C” to learn about drug side effects, proper use and ...