Search Results 821-830 of 37919 for Two-phase

  1. A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection - Mayo Clinic

    Additionally patients with hematologic malignancies will be evaluated on a treatment schedule of five days in a row with two weeks off. Participation ...

  2. Breast cancer types: What your type means - Mayo Clinic

    Some breast cancer cells make too much of a protein called human epithelial growth factor-receptor 2, also called HER2. Healthy breast cells make some HER2 ...

  3. KTX-100 MMSET Catalytic Inhibitor that Suppresses H3K36me2 in Patients with Relapsed and Refractory Multiple Myeloma - Mayo Clinic

    The purpose of this study is to determine the maximum tolerated dose (MTD) and schedule and/or a recommended Phase 2 dose (RP2D) and schedule of KTX-1001 for ...

  4. Clinical trials - Oncology (Medical)

    ... phase 2 dose (RP2D) 1.1.2 To evaluate the safety and tolerability of this ... In Part 2, the step-up dose identified in Part 1 will be used followed by ...

  5. A Study of TAK-981 in Combination with Rituximab in Participants with Relapsed/Refractory (r/r) CD20-positive (CD20+) Non-Hodgkin Lymphoma (NHL) - Mayo Clinic

    ... Phase 1b, and to evaluate the effectiveness of TAK-981 in combination with rituximab in r/r CD20+ NHL in Phase 2. Participation eligibility. Participant ...

  6. Novel HSF1 Pathway Inhibitor NXP800 In Patients with Advanced Cholangiocarcinoma - Mayo Clinic

    The purpose of this trial is to determine the maximum tolerated dose (MTD)/recommended Phase 2 dose for NXP800. Participation eligibility. Participant ...

  7. Phase I/II Study Of The Combination Of Blinatumomab And Asciminib In Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia - Mayo Clinic

    Study phase. 2. During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase ...

  8. Pneumonia Clinical Trials

    Phase 2: The primary objective of the study is to evaluate the clinical efficacy of sarilumab relative to the control arm in adult patients hospitalized ...

  9. Gastrointestinal Stromal Tumor Clinical Trials - Mayo Clinic Research

    The purpose of this Phase 1/2 master protocol study is to evaluate if DCC-3009 is safe, tolerable and works effectively in the treatment of GIST. The study will ...

  10. Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck - Mayo Clinic

    Study phase. 2/3. During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase ( ...