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  1. Entacapone (oral route) - Side effects & dosage - Mayo Clinic

    In patients with Parkinson's disease, there is not enough dopamine in some parts of the brain. Entacapone helps levodopa last longer by blocking a substance ...

  2. KTX-100 MMSET Catalytic Inhibitor that Suppresses H3K36me2 in Patients with Relapsed and Refractory Multiple Myeloma - Mayo Clinic

    The purpose of this study is to determine the maximum tolerated dose (MTD) and schedule and/or a recommended Phase 2 dose (RP2D) and schedule of KTX-1001 ...

  3. A Study to Determine Safety, Pharmacokinetics and Pharmacodynamics of Intravenous TKM 080301 in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients - Mayo Clinic

    After the determination of the maximum tolerated dose this dose will be utilized in an expansion cohort or subjects with refractory neuroendocrine tumors ...

  4. Liver Tumors Clinical Trials - Mayo Clinic Research

    The purpose of this study is to demonstrate that microwave ablation (MWA) of up to 3 hepatic metastases, each with a maximum diameter of ≤ 2.5 cm will ...

  5. Clinical trials - Oncology (Medical)

    ... determine the maximum tolerated dose (MTD), identify a recommended phase 2 dose (RP2D) and preferred schedule, and assess preliminary anti-tumor activity.

  6. Neurology - Clinical trials - Mayo Clinic

    The purpose of phase 1 of this trial is to determine the maximum tolerated dose of temozolomide followed by selinexor in recurrent glioblastoma patients as ...

  7. Neurology - Clinical trials

    The purpose of phase 1 of this trial is to determine the maximum tolerated dose of temozolomide followed by selinexor in recurrent glioblastoma patients as ...

  8. Amlodipine and olmesartan (oral route) - Side effects & dosage - Mayo Clinic

    This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce ...

  9. A Study to Evaluate the Effectiveness, Safety and Way in Which the Body Processes REGN3500 in Adults with Moderate-to-Severe Atopic Dermatitis - Mayo Clinic

    ... maximum duration for screening. Documented recent history (within 6 months ... maximum duration recommended by the product prescribing information ...

  10. A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Effectiveness of AMG 397 in Subjects With Multiple Myeloma, NHL, and AML - Mayo Clinic

    The purpose of this study is to evaluate the safety and tolerability of AMG 397 by estimating the maximum tolerated doses (MTDs) and/or biologically active ...