Search Results 71-80 of 12455 for Somatic

  1. Clinical trials - Oncology (Medical)

    Germline and somatic variants are changes in genes found using cancer genomic tests. Cancer genetic/genomic testing is a series of tests that find specific ...

  2. Publications - David S. Viswanatha, M.D. - Mayo Clinic

    Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasms. ... Somatic TP53 single ...

  3. Clinical trials - Oncology (Medical)

    Germline and somatic variants are changes in genes found using cancer genomic tests. Cancer genetic/genomic testing is a series of tests that find specific ...

  4. Immunology Program - Robert and Arlene Kogod Center on Aging

    These changes include somatic mutations, failure in DNA repair, epigenetic signatures including cellular senescence and exhaustion, and organelle dysfunction.

  5. CAR-T Cell Therapy Program - Clinical trials

    Germline and somatic variants are changes in genes found using cancer genomic tests. Cancer genetic/genomic testing is a series of tests that find specific ...

  6. A Study of Niraparib Combined with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone to Treat Metastatic Prostate Cancer - Mayo Clinic

    ... somatic Homologous Recombination Repair (HRR) gene-mutated mCSPC provides superior effectiveness in improving radiographic progression-free survival (rPFS) ...

  7. Novel proton therapy technique shows promise with resistant cancer cells - Mayo Clinic

    Germline and somatic alterations in these genes are also commonly observed in multiple other cancer types." Dr. Mutter and his colleagues found an up to ...

  8. Clonal hematopoiesis clinic stratifies risk for patients with cancer

    Clonal hematopoiesis is the acquisition of somatic pathogenic variants in hematopoietic stem and progenitor cells. These variants can expand over time, and ...

  9. Zhifu Sun, M.D. - Mayo Clinic Faculty Profiles

    Unlike somatic mutations with a low recurrence frequency in most cancers, DNA methylation changes occur more universally. These cancer hallmarks can be ...

  10. Human developmental disorders arising from mutations in epigenetic regulator genes - Research

    Disruption of epigenetic regulator genes in cancer is common. This disruption typically manifests as the loss of both gene copies in somatic cells. But single ...