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  1. A Study to Evaluate Pluripotent Stem Cell Models for Spinal Muscular Atrophy (SMA) Patients - Mayo Clinic

    By comparing the gene expression of motor neurons derived from iPSC cells of phenotypically discordant Spinal Muscular Atrophy (SMA) sibling pairs and ...

  2. Chemotherapy For Clinical Trials - Mayo Clinic Research

    The goal is to prove feasibility as well as safety of this approach. We will test adaptive therapy in 35 metastatic breast cancer patients diagnosed with ER+ ...

  3. Precision medicine for breast cancer - Doctors & Departments - Mayo Clinic

    Learn how genetic testing can help customize your cancer treatment plan. Precision medicine is improving breast cancer diagnosis, treatment and prevention.

  4. Breast cancer - Doctors and departments - Mayo Clinic

    Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens ...

  5. A Study to Evaluate the Use of AR-42 (Histone Deacetylase Inhibitor) in the Treatment of Vestibular Schwannoma and Meningioma - Mayo Clinic

    AR-42 is a small molecule which crosses the blood brain barrier (BBB) in rodents, but the investigators are not certain yet if it will penetrate human ...

  6. Precision medicine for breast cancer - Doctors & Departments - Mayo Clinic

    Learn how genetic testing can help customize your cancer treatment plan. Precision medicine is improving breast cancer diagnosis, treatment and prevention.

  7. NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of AKCEA-TTR-LRx in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy - Mayo Clinic

    Evaluating the efficacy of ION-682884 after administration for 65 weeks, as compared to the historical control of the placebo cohort (inotersen) in the NEURO- ...

  8. Evaluating Kidney Stones To Determine If They Lead to Kidney Disease - Mayo Clinic

    About this study. We hypothesize that clinical studies to investigate the role of individual proteins in kidney stone pathogenesis have likely been ...

  9. Clinical trials - Oncology (Medical)

    Cohort C: Triple-negative breast cancer (TNBC);; Cohort D: Platinum-resistant/refractory epithelial ovarian, primary peritoneal, or fallopian tube cancer ( ...

  10. Clinical trials - Oncology (Medical)

    Romidepsin and lenalidomide may stop the growth of cancer cells by blocking enzymes needed for cell growth. Giving rituximab together with romidepsin and ...