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  1. An Expanded Access Study of Sofosbuvir Combined with Ribavirin and Either with or without Pegylated Interferon for Treating Aggressive Post-Transplant Hepatitis C - Mayo Clinic

    The purpose of this study, is to open expanded access at specific clinical sites at the request of an investigator for the treatment of individual subjects for ...

  2. Establishment of Disease Ranges of Selected Markers and Ratios for the Detection of OTC Deficiency and CPS Deficiency using Newborn Blood Spots - Mayo Clinic

    About this study. The purpose of this study is to obtain and analyze existing newborn screening data from previously identified patients with a confirmed ...

  3. A Study to Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1 - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. A Study of Autoimmune Functions in Patients with Myocarditis - Mayo Clinic

    About this study. The purpose of this research is to study immune cells called T cells and monocytes (types of blood cells that fight infection and can also ...

  5. Retrospective Review of Radiological Findings of Uterine Leiomyosarcoma in Comparison with Those of Atypical Leiomyoma - Mayo Clinic

    The purpose of this study is to retrospectively review the imaging findings of the uterine leiomyosarcoma and compare with those of atypical leiomyoma.

  6. PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial

    24-week study to evaluate the efficacy and safety of macitentan for the treatment of portopulmonary hypertension. Participation eligibility. Participant ...

  7. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity - Mayo Clinic

    The purpose of this study is to determine if the change in pulmonary vascular compliance with positional changes (upright, supine, and Trendelenburg position) ...

  8. ORC-13661 for the Prevention of Drug-Induced Hearing Loss in Intravenous Amikacin Treatment of Non-Tuberculous Mycobacterium Disease - Mayo Clinic

    The purpoes of this study is to evaluate the safety of ORC-13661 and its ability to significantly mitigate or prevent hearing loss in patients being treated ...

  9. A Study to Determine the Effect of Endogenous Glucagon-Like Peptide-1 on Active Intestinal Glucose Transport and Intestinal Permeability - Mayo Clinic

    The purpose of this study is to determine the effect of endogenous glucagon-like peptide-1 on active intestinal glucose transport and on intestinal permeability ...

  10. Feasibility of Use of BariCare App in Pre-transplant Population - Mayo Clinic

    This current study aims to evaluate the efficacy of engagement modules in assisting patients who are candidates for renal and liver transplantation make ...