Search Results 591-600 of 15133 for alt

1. A Study of Carboplatin, Cabazitaxel and Abiraterone in High Volume Metastatic Castration Sensitive Prostate Cancer (CASCARA) - Mayo Clinic

   In the absence of liver metastases, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) < 2.5 x ULN. If the patient has liver metastases, ALT ...

2. A Study of Zetomipzomib (KZR-616) in Patients With Autoimmune Hepatitis (PORTOLA) - Mayo Clinic

   * Screening ALT values that are 1.25 to 10 times the upper limit of the normal range (ULN) * Liver biopsy results with Ishak score (modified HAI) ≥5/18 ...

3. Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors - Mayo Clinic

   Adequate hepatic function: AST and ALT <2.5 x ULN, Total and Direct Bilirubin <1.5 x ULN. However, in the presence of liver metastases, AST and ALT must be <5 x ...

4. Study To Evaluate The Efficacy And Safety Of Elafibranor In Patients With Primary Biliary Cholangitis (PBC) And Inadequate Response To Ursodeoxycholic Acid - Mayo Clinic

   'AIH-PBC overlap syndrome' is based upon fulfilment of the Paris criteria (Chazouilléres 1998)for both AIH (ALT ≥5x ULN; IgG ≥2x ULN or smooth muscle ...

5. Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair - Mayo Clinic

   Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN); Thyroid-stimulating hormone (TSH) within normal limits ...

6. Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas - Mayo Clinic

   Alanine amino transferase (ALT) and aspartate aminotransferase (AST) =< 2.5 X ULN. Concomitant elevations in bilirubin and AST/ALT above 1.0 x ULN (upper limit ...

7. First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors - Mayo Clinic

   Aspartate aminotransferase (AST/SGOT), alanine aminotransferase (ALT/SGPT) and alkaline phosphatase ≤ 2.5 × ULN. ... *Patients receiving immunotherapy should ...

8. Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation? - Mayo Clinic

   Elevation in AST, ALT, Bilirubin or alkaline phosphatase more than five times the upper limit of normal. Participating Mayo Clinic locations. Study statuses ...

9. PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Subjects With Primary Sclerosing Cholangitis - Mayo Clinic

   ALT: males > 250 IU/L and females > 200 IU/L. Total Bilirubin and Direct Bilirubin; above the allowed cut-offs, as determined by the mean Screening and pre ...

10. A Study of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) in Combination With Carboplatin Plus (+) Nab-Paclitaxel Compared With Carboplatin + Nab-Paclitaxel in Participants With Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower130) - Mayo Clinic

    AST, ALT, and alkaline phosphatase ≤ 2.5 x ULN, with the following exceptions: Patients with documented liver metastases: AST and/or ALT ≤ 5 x ULN; ...