Search Results 51-60 of 17246 for Irinotecan

  1. MicroOrganoSphere Drug Screen Pilot Trial in Colorectal Cancer (CRC) - Mayo Clinic

    ... irinotecan, 5-FU/Xeloda, Bevacizumab, Panitumumab or Cetuximab, Lonsurf, Regorafenib and Pembrolizumab or Nivolumab) in < 14 days. The secondary objective ...

  2. Ziv-aflibercept (intravenous route) - Side effects & uses - Mayo Clinic

    Ziv-aflibercept injection is given together with other medicines (eg, fluorouracil, irinotecan, leucovorin) to treat advanced cancer of the colon or rectum.

  3. Stage 4 (metastatic) colon cancer - Diagnosis and treatment - Mayo Clinic

    Another first line treatment option is 5-fluorouracil (5-FU), leucovorin and irinotecan, known as FOLFIRI. There are other chemotherapy combinations ...

  4. Cellular Responses to DNA Damage Induced by Topoisomerase Poisons - Anticancer Drug Action Laboratory - Mayo Clinic Research

    This enzyme is also the target of the anti-cancer drugs irinotecan, topotecan, MM398, PLX038 and CBX-12, along with a growing number of antibody-drug ...

  5. A Study Evaluating Effectiveness and Safety of FFX Versus Combination of CPI-613 with mFFX in Patients with Metastatic Adenocarcinoma of the Pancreas - Mayo Clinic

    Unwilling or unable to avoid the concomitant use of strong CYP3A4 inducers or inhibitors during treatment with irinotecan. A marked baseline prolongation of ...

  6. Clinical trials - Oncology (Medical)

    Drugs used in chemotherapy regimens such as UH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, and irinotecan) and ICE/Cyclo/Topo ...

  7. A Study to Analyze Onvansertib Treatment in Patients with Metastatic Pancreatic Ductal Adenocarcinoma - Mayo Clinic

    This study aims to assess the efficacy of onvansertib in combination with nanoliposomal irinotecan (nal-IRI), leucovorin, and fluorouracil (5-FU) for ...

  8. Clinical trials - Oncology (Medical)

    Drugs used in chemotherapy regimens such as UH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, and irinotecan) and ICE/Cyclo/Topo ...

  9. Clinical trials - Oncology (Medical)

    The purpose of this study is to investigate the antitumor activity of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with ...

  10. Medulloblastoma Clinical Trials - Mayo Clinic Research

    Drugs used in chemotherapy, such as temozolomide and irinotecan hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the ...