Search Results 51-60 of 9808 for Inhibition

  1. Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma - Mayo Clinic

    Clinical Trials · Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma · More about research at Mayo ...

  2. AKT Inhibitor MK2206, Combined with Bendamustine Hydrochloride, and Rituximab for Treating Patients who have Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma - Mayo Clinic

    Akt inhibitor MK2206 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as ...

  3. Targeting Mesotrypsin in Breast, Prostate, Pancreatic and Lung Cancers - Proteases in Cancer Laboratory - Mayo Clinic Research

    ... inhibition by many inhibitors of other trypsins. Our lab has created prototype mesotrypsin inhibitors with improved affinity by using site-directed ...

  4. Study of Bcl-2 Inhibitor BGB-11417 in Participants With Mature B-Cell Malignancies - Mayo Clinic

    Study of Bcl-2 Inhibitor BGB-11417 in Participants With Mature B-Cell Malignancies · Overview · Participation eligibility · Participating Mayo Clinic locations.

  5. Bicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate Cancer - Mayo Clinic

    Akt inhibitor MK2206 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether bicalutamide is more ...

  6. Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL - Mayo Clinic

    TP 0903 was shown to induce apoptosis in CLL B-cells taken directly from patients.TP-0903 was equally potent against CLL cells regardless of risk-factor. TP- ...

  7. A Study to Evaluate the Use of AR-42 (Histone Deacetylase Inhibitor) in the Treatment of Vestibular Schwannoma and Meningioma - Mayo Clinic

    The purpose of this study is to assess the use of AR-42 in adult patients undergoing NF2-tumor removal. AR-42 is a small molecule which crosses the blood brain ...

  8. C1 Esterase Inhibitor Recombinant (Intravenous Route) Before Using - Mayo Clinic

    Appropriate studies have not been performed on the relationship of age to the effects of C1 esterase inhibitor recombinant in the geriatric population. Safety ...

  9. GMCI Plus Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  10. KTX-100 MMSET Catalytic Inhibitor that Suppresses H3K36me2 in Patients with Relapsed and Refractory Multiple Myeloma - Mayo Clinic

    The purpose of this study is to determine the maximum tolerated dose (MTD) and schedule and/or a recommended Phase 2 dose (RP2D) and schedule of KTX-1001 for ...