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  1. A Study to Evaluate Sacubitril-Valsartan for Left Ventricular Reverse Remodeling in Adults with Congenital Heart Abnormality - Mayo Clinic

    The purpose of this study is to determine the optimal medical therapy to improve left ventricular (LV) function. Improvement in LV function has the potential to ...

  2. A Study of the Effect of Colesevelam on Glucose Metabolism in Patients with Type 2 Diabetes - Mayo Clinic

    The purpose of this study is to determine the metabolic effects of Colesevelam, particularly for the ability to lower blood sugar after a meal in type 2 ...

  3. Development of Skeletal Muscle Fibers from Patient-Derived Induced Pluripotent Stem Cells (iPSCs) - Mayo Clinic

    The study will also use skin fibroblasts as source of DNA to investigate for research purpose the genetic defect causing the myopathy, and test in future ...

  4. A Study Comparing Effectiveness and Safety of SPIRA-A Anterior Lumbar Interbody Fusion Device to PEEK Anterior Lumbar Interbody Fusion Cage with rhBMP-2 in Instrumented Lumbar Fusions - Mayo Clinic

    Sponsor Protocol Number: SPA-2018. About this study. The purpose of this study is to evaluate if SPIRA-A Anterior Lumbar Interbody Fusion Device is equivalent ...

  5. Acoustic Resonance Therapy (ART) to Cognitive Behavioral Therapy for Insomnia (CBT-I) for Treating Patients with Moderate to Severe Chronic Insomnia - Mayo Clinic

    Acoustic Resonance Therapy (ART) to Cognitive Behavioral Therapy for Insomnia (CBT-I) for Treating Patients with Moderate to Severe Chronic Insomnia · Overview.

  6. A Study Using Prothrombin Complex Concentrate versus Fresh Frozen Plasma for Post Cardiopulmonary Bypass Surgery Clotting Problems and Bleeding - Mayo Clinic

    The purpose of this study is to directly compare prothrombin complex concentrate to fresh frozen plasma for microvascular bleeding and factor-mediated clotting ...

  7. Transcutaneous Spinal Cord Stimulation Enabling Reflex Motor Evoked Responses with Spina Bifida - Mayo Clinic

    About this study. The purpose of this study is to characterize the motor function deficits specific to muscle weakness, intra and interlimb coordination, ...

  8. Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults with Partial Deafness - Mayo Clinic

    About this study. The purpose of this feasibility study is to evaluate whether low-frequency acoustic hearing sensitivity can be preserved in newly ...

  9. Is physical exercise associated with significant changes in the frequency or burden of spikes on EEG in children with epilepsy? - Mayo Clinic

    About this study. This study hypothesises that physical exercise in children with epilepsy will be associated with a significant reduction in interictal ...

  10. A Study of the Effectiveness and Safety of Ofatumumab Compared to Teriflunomide for the Treatment of Patients with Relapsing Multiple Sclerosis - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...