Search Results 581-590 of 17275 for egfr

  1. A Study Of Tucatinib Plus Trastuzumab Deruxtecan In HER2+ Breast Cancer - Mayo Clinic

    Any investigational HER2/epidermal growth factor receptor (EGFR) or HER2 tyrosine kinase inhibitor (TKI) (e.g., afatinib) at any time previously; ...

  2. A Phase 2a Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases - Mayo Clinic

    Subprotocol A and B: Estimated glomerular filtration rate (eGFR) of < 45 mL per minute per 1.73 m^2 of body surface area (calculated using the Modification ...

  3. Oral and Intravenous Methadone for Analgesia in Cardiac Surgery - Mayo Clinic

    ... eGFR < 30mL/min, documented cirrhosis, intolerance to methadone, subsequent surgeries after index surgery. Note: Other protocol defined Inclusion/Exclusion ...

  4. Mouth Cancer Clinical Trials

    The purpose of this study is to demonstrate the safety and tolerability of JAB-3312 in combination with anti-PD-1 mAb or MEKi or KRASi or EGFR-TKI in patients ...

  5. A Study to Evaluate ION251 to Treat Patients with Relapsed/Refractory Multiple Myleoma - Mayo Clinic

    Estimated glomerular filtration rate (eGFR, by CKD-EPI equation < 50 mL/min/1.73 m^2 );; Urine albumin creatinine ratio > 100 mg/g. Active infection ...

  6. Glioblastoma Clinical Trials - Mayo Clinic Research

    ... (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma multiforme (GBM) expressing EGFR alterations ...

  7. Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation For Children, Adolescents, And Young Adults With Acute Leukemia Or Myelodysplastic Syndrome - Mayo Clinic

    clearance method (iothalamate or other molecule per institutional standard). - Note: Estimated GFR (eGFR) from serum creatinine, cystatin C or other estimates

  8. Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D) - Mayo Clinic

    The purpose of this multi-center event-driven study in participants with anemia associated with chronic kidney disease (CKD) to evaluate the safety and efficacy ...

  9. A Study to Evaluate Hepcidin Mimetic in Patients With Polycythemia Vera - Mayo Clinic

    Estimated Glomerular Filtration Rate (eGFR) <40 mL/min/1.73 m^2;; Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) ≥ 2.5 × upper limit of ...

  10. A Study to Evaluate Abemaciclib to Treat Advanced Bone and Soft Tissue Sarcoma Identified as Having CDK Pathway Alteration - Mayo Clinic

    Estimated Creatinine Clearance (CrCl) ≥ 30 mL/min (Cockcroft-Gault), estimated glomerular filtration rate (eGFR) ≥ 30 mL/min/1.73 m^2 (MDRD or CKD-EPI ...