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1. Phase 3 Study Of Taletrectinib Vs Placebo As An Adjuvant Therapy In ROS1 Positive NSCLC (TRUST-IV) - Mayo Clinic

   The study compares taletrectinib (study drug) versus placebo (sugar pill) in patients with ROS1-fusion positive stage IB, II, IIIA NSCLC. The study will ...

2. Academics - Find a Program at Mayo Clinic College of Medicine & Science

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3. Extent and Severity of Intravascular Volume Overload in Relation to Right Heart Catheter Hemodynamic Parameters - Mayo Clinic

   The purpose of this study is to assess the extent and severity of plasma volume expansion and overload in patients requiring ultrafiltration/dialysis and ...

4. A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622 - Mayo Clinic

   About this study. This is an open-label extension study to Study 200622.In this study subjects from Study 200622 will be continued on 4-weekly dosing with ...

5. Lenalidomide for Myelodysplastic Syndrome Refractory to Hypomethylating Agents - Mayo Clinic

   The purpose of this study is to determine the proportion of confirmed responses (complete response, partial response), and hematologic improvement as defined by ...

6. Akt Inhibitor MK-2206 and Anastrozole With or Without Goserelin Acetate in Treating Patients With Stage II-III Breast Cancer - Mayo Clinic

   Estrogen can cause the growth of breast cancer cells. Hormone therapy using anastrozole and goserelin acetate may fight breast cancer by blocking the use of ...

7. Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

   This is a multicenter, international, double-blind study of the administration of mavacamten in participants with symptomatic obstructive HCM (oHCM).

8. Generated Lymphoblastoid Cell Lines - Clinical Trials

   The purpose of this study is to generate lymphoblastoid cell lines (LCLs) from whole blood or peripheral blood mononuclear cells (PBMCs) to serve as models of ...

9. A Study to Create a Registry for Users of Opsumit - Mayo Clinic

   The purpose of this registry is to characterize the safety profile (especially potentially serious risks to the liver) and describe clinical characteristics and ...

10. Rigorous science in regenerative medicine - Regenerative Neurosurgery and Neuro-Oncology Lab - Mayo Clinic Research

    Investigators in the Regenerative Neurosurgery and Neuro-Oncology Lab have cast doubts on commonly used markers to gauge stem cell plasticity.