Search Results 501-510 of 37850 for Two-phase

  1. Phase 1 Trial to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Splicing Modulator H3B-8800 for Subjects With Myelodysplastic Syndromes, Acute Myeloid Leukemia, and Chronic Myelomonocytic Leukemia - Mayo Clinic

    The primary objectives of the study are to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of H3B-8800 administered orally in ...

  2. Execute _Preview Minutes_ on HM00000252

    The Biological Hazard Application, Bios00002062, for "A Phase 1b/2 Study of AZD0120 (Also Known as. GC012F), a Chimeric Antigen Receptor T Cell Therapy ...

  3. A Study of MT-0169 in Participants With Relapsed or Refractory Multiple Myeloma or non-Hodgkin Lymphoma - Mayo Clinic

    Recommended phase 2 dose means that dose is judged to be the most optimal for future study in patients with your disease. The study will also examine how the ...

  4. Cholangiocarcinoma (Bile Duct Cancer) Clinical Trials - Mayo Clinic Research

    The study is divided into two parts: single agent FT-2102 followed by combination therapy. ... Phase 2 investigation of clinical activity in up to 4 cohorts.

  5. Rectal Cancer Clinical Trials - Mayo Clinic Research

    Giving chemotherapy after surgery may kill any remaining tumor cells. PURPOSE: This randomized phase II trial is studying two different regimens of neoadjuvant ...

  6. Efficacy, Safety And Tolerability Of VS-01 In Adult Patients With Acute-on-Chronic Liver Failure And Ascites (UNVEIL-IT)® - Mayo Clinic

    A Phase 2, multi-center, randomized, controlled, open-label study to evaluate the effects of the intraperitoneal, liposomal formulation VS-01 in patients ...

  7. Study Of 225Ac-ABD147 To Establish Optimal Dose In Patients With SCLC And LCNEC Of The Lung That Previously Received Platinum-based Chemotherapy - Mayo Clinic

    The study has 2 parts, Phase 1a and Phase 1b. The goal of Phase 1a is to gather safety, PK and initial efficacy data for 225Ac-ABD147 to better understand best ...

  8. Neurology - Clinical trials

    The purpose of phase 2 of this trial is to evaluate the effectiveness of sequentially administering temozolomide and selinexor in recurrent glioblastoma as ...

  9. Rectal cancer - Survival rates - Mayo Clinic

    Localized cancer is considered early-stage cancer and includes stages 0, 1 and most stage 2 colorectal cancers. Survival rate for people with localized ...

  10. SL-401 in Advanced, High Risk Myeloproliferative Neoplasms (Systemic Mastocytosis, Advanced Symptomatic Hypereosinoophic Disorder, Chronic Myelomonocytic Leukemia) - Mayo Clinic

    The Stage 2 portion will enroll up to 18 patients with each of the 4 myeloproliferative malignancies: SM, PED, MF, and CMML. In entirety, the Stage 2 portion ...