Search Results 491-500 of 14957 for alt

  1. Study of SBP-101 in Pancreatic Cancer - Clinical Trials

    ... (ALT) ≤2.5 x upper limit of normal (ULN) (if no hepatic metastases). If hepatic tumor involvement, AST and ALT ≤5 x ULN, Bilirubin ≤1.5 x ULN ...

  2. IFX_HU2.0 As An Adjunctive Therapy To Pembrolixumab In Checkpoint Inhibitor Naive Subjects With Advanced Or Metastatic Merkel Cell Carcinoma - Mayo Clinic

    Serum Alanine Aminotransferase (ALT) ≤ 1 - 3 x ULN; Serum Aspartate Aminotransferase (AST) ≤ 1 - 3 x ULN; Alkaline Phosphatase (ALP) ≤ 1 - 2.5 x ULN; Gamma ...

  3. A Study to Evaluate T-DM1 With or Without Abemaciclib in Women and Men with HER2-positive Advanced or Metastatic Breast Cancer - Mayo Clinic

    NOTE: If liver metastases are present, AST and ALT ≤ 5 x ULN are acceptable. Prothrombin time (PT)/international normalized ratio (INR)/partial ...

  4. A Study to Assess Metformin Hydrochloride in Patients With Atypical Hyperplasia or In Situ Breast Cancer to Placebo in Decreasing Atypical Cells in Patients With Atypical Hyperplasia or in Situ Breast Cancer - Mayo Clinic

    Alanine transaminase (ALT) ≤ 3 x ULN. Negative pregnancy test done ≤ 7 days prior to registration/randomization, for women of childbearing potential only ...

  5. A Study to Evaluate RGLS4326 to Treat Autosomal Dominant Polycystic Kidney Disease - Mayo Clinic

    Alanine aminotransferase (ALT) < 1.5 x ULN;; Aspartate aminotransferase (AST) < 1.5 x ULN;; Alkaline phosphatase (ALP) < 1.5 x ULN;; Gamma-glutamyl transferase ...

  6. Safety, Tolerability, and Efficacy of GS 9674 in Adults With Primary Biliary Cholangitis Without Cirrhosis - Mayo Clinic

    Alanine aminotransferase (ALT) > 5 x ULN; Total bilirubin > 2 x ULN; International normalized ratio (INR) > 1.2 unless on anticoagulant therapy; Other causes ...

  7. Expanding Liver Transplant Immunosuppression Minimization Via Everolimus - Mayo Clinic

    ... (ALT)\>60 U/L 13. Pregnant on enrollment or plan to become pregnant during the study period. 14. Participation in another clinical trial that would interfere ...

  8. Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis

    Participation eligibility · Serum creatinine clearance < 50 ml/min (as calculated by the Cockcroft-Gault formula); · Alanine Aminotransferase (ALT) > 2x the ...

  9. A Study to Evaluate the Effectiveness and Safety of Aramchol Versus Placebo in Subjects With NASH (ARMOR) - Mayo Clinic

    Histologically documented liver cirrhosis (fibrosis stage 4). · Inability or unwillingness to undergo a liver biopsy. · Abnormal synthetic liver function. · ALT or ...

  10. S1406 A Phase II Study of Irinotecan and Cetuximab with or without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer - Mayo Clinic

    AST and ALT ≤ 2.5 x institutional upper limit of normal (IULN) or ≤ 5 x IULN if liver metastases are present within 14 days; Serum creatinine ≤ 1.5 x IULN ...