Search Results 491-500 of 17401 for Oncogene

  1. A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors - Mayo Clinic

    - Endometrial cancers with specific concurrent oncogenic alterations - A history of known active or suspected - Diabetes mellitus Type 1 or - Diabetes ...

  2. Medical Research & Education - Mayo Clinic News Network

    Antibody-drug conjugates are targeted cancer therapies. They deliver potent drugs directly into cancer cells while minimizing harm to healthy tissue. These ...

  3. Clinical trials - Oncology (Medical)

    Rochester, Minn., Jacksonville, Fla. The purpose of this study is to look at the effects cancer and melanoma have on the immune cells found in lymph nodes. A ...

  4. Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin for First-Line Treatment of Patients With Advanced NSCLC Without Actionable Genomic Alterations - Mayo Clinic

    driver oncogenes with approved therapies (actionable genomic alterations). - ECOG PS of 0 or 1 - Archival tumour tissue collected prior to signing of ICF - ...

  5. Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients with Resected Pancreatic Cancer (the "Apact" Study) - Mayo Clinic

    ... oncogenic pathways. In this article, we describe the design and rationale for the CanStem111P clinical trial, a multicenter, randomized, open-label, Phase ...

  6. Publications - Yael N. Kusne, M.D., Ph.D. - Mayo Clinic

    Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFalpha in glioblastoma. Sci Signal. 2014 Aug 12; 7 (338): ...

  7. Oncology (Medical) - Clinical trials

    There is evidence that colonic inflammation plays a major role in colon polyp and colorectal cancer development. For example, inflammatory bowel disease is a ...

  8. Clinical trials - Oncology (Medical)

    Rochester, Minn. This is an open label, phase I/II, multi-center study in adult participants with metastatic hormone sensitive prostate cancer (mHSPC) and with ...

  9. Publications - Erinn Downs, D.O. - Mayo Clinic

    Oncogene. 2012 Apr 26; 31 (17):2222-36 Epub 2011 Sept 26. View PubMed; Navaneethan U, Venkatesh PG, Downs-Kelly E, Shen B. Isospora belli superinfection in a ...

  10. A Study To Investigate ALE.P03 As Monotherapy In Adult Patients With Selected Advanced Or Metastatic CLDN1+ Solid Tumors - Mayo Clinic

    * Patients with actionable oncogenic drivers: received feasible targeted therapy. Applicable for Phase I Dose Escalation, Phase I RDE and Phase II ...