Search Results 31-40 of 35897 for Two-phase

  1. Phase 1/2 Study of BDTX-1535 in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations - Mayo Clinic

    BDTX-1535-101 is an open-label, Phase 1 dose escalation and Phase 2 multiple cohort study designed to evaluate the safety, pharmacokinetics (PK), optimal dosage ...

  2. A Study To Evaluate The Adverse Events, And Efficacy Of Intravenous (IV) Of Telisotuzumab Adizutecan In Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab In Adult Participants With Metastatic Colorectal Cancer - Mayo Clinic

    This study will be divided into two stages, with the first stage treating participants with increasing doses of telisotuzumab adizutecan with FOLFOX and ...

  3. Phase Ib Study of Axatilimab in Combination with Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer - Mayo Clinic

    Phase Ib Study of Axatilimab in Combination with Olaparib in BRCA1/2 and PALB2- Associated Metastatic HER2-negative Breast Cancer · More about research at Mayo ...

  4. Phase 1/2 Study of AG-221 in Subjects With Advanced Hematologic Malignancies With an IDH2 Mutation - Mayo Clinic

    The study includes a dose escalation phase to determine the maximum tolerated dose (MTD) and/or the recommended Phase 2 dose (RP2D) and an expansion phase to ...

  5. A Study to Compare CMP-001 Combined with Nivolumab to Nivolumab Alone in Advanced Melanoma Subjects - Mayo Clinic

    The purpose of this two-phase study is to compare CMP-001 intratumoral (IT) and nivolumab intravenous (IV) compared to nivolumab monotherapy administered to ...

  6. Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) - Mayo Clinic

    Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION). Print ...

  7. Clinical trials - Oncology (Medical)

    The study will be performed in two phases: Phase I will be performed for biologic validation of marker candidates from a discovery cohort and phase II will ...

  8. Clinical trials - Oncology (Medical)

    ... Phase 2 dose (RP2D) and schedule of KTX-1001 for ... The first part of the study includes the first two phases of therapy: Induction and Consolidation.

  9. Clinical trials - Oncology (Medical)

    ... phase II dose (RP2D of APG2575 in combination with ... The first part of the study includes the first two phases of therapy: Induction and Consolidation.

  10. PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study - Mayo Clinic

    Study phase. 2. During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase ...