Search Results 381-390 of 17281 for egfr

  1. Study of ALXN2220 Versus Placebo in Adults With ATTR-CM - Mayo Clinic

    * Renal failure requiring dialysis or an eGFR \< 20 mL/min/1.73 m2 at Screening * Polyneuropathy with PND score IV. Note: Other protocol defined Inclusion ...

  2. Safety and Efficacy of Selonsertib, GS-0976, GS-9674, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) - Mayo Clinic

    Estimated glomerular filtration rate (eGFR) ≥ 60 mL/min, as calculated by the Cockcroft-Gault equation; HbA1c ≤ 9.5%; Alanine aminotransferase (ALT) < 5 x ...

  3. A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma - Mayo Clinic

    ... EGFR-targeted antibody therapy is allowed regardless of the prior treatment settings. For Phase II, Arms 1 and 2, prior cetuximab or other EGFR-targeted ...

  4. Study to Evaluate the Effectiveness and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy - Mayo Clinic

    eGFR ≥45 mL/min per 1.73 m2 and ≤90 mL/min per 1.73 m2 using the Chronic Kidney Diseae Epidemiology Collaboration (CKD-EPI) formula. Willing and able to ...

  5. A Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495) - Mayo Clinic

    ... EGFR or B-Raf mutations AND absence of ALK or ROS1 gene rearrangements). Has measurable disease per RECIST 1.1 as assessed by the local site investigator ...

  6. Publications - Ande M. Rumilla, M.D. - Mayo Clinic

    2016 Oct 20; 17(1):814. View PubMed; Leventakos K, Kipp BR, Rumilla KM, Winters JL, Yi ES, Mansfield AS. S768I Mutation in EGFR in Patients with Lung Cancer.

  7. Phase III Study Of Datopotamab Deruxtecan Versus Docetaxel In Previously Treated TROP2-positive Advanced Or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations - Mayo Clinic

    * Participants must have documented negative test results for epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and ROS proto ...

  8. A Study to Evaluate the Safety and Effectiveness of BMS-986036 (pegbelfermin) in Adults with Nonalcoholic Steatophepatitis (NASH) and Compensated Liver Fibrosis - Mayo Clinic

    Estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m2 according to the Modification of Diet in Renal Disease equation. Evidence of significant ...

  9. Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia - Mayo Clinic

    Serum creatinine > 1.5 x ULN or eGFR 160 mmHg and/or diastolic blood pressure > 95 mmHg). Baseline standard 12-lead ECG that demonstrates clinically ...

  10. Subcutaneous Furosemide In Acute Decompensated Heart Failure Pilot - Mayo Clinic

    Participation eligibility · Severe renal dysfunction (Estimated Glomerular Filtration Rate (eGFR)< 30 ml/min/1.73m2) · Requirement for inotropes (other than ...