Search Results 381-390 of 37489 for Two-phase

  1. Colon Cancer Clinical Trials - Mayo Clinic Research

    The primary purpose of this study for Step 2: To assess the anti-tumour activity of MEN1611 in combination with cetuximab in patients with PIK3CA mutated ...

  2. Breast Cancer Surgery Clinical Trials - Mayo Clinic Research

    Implant-based breast reconstruction is frequently achieved in two-stages. The first stage consists of the placement of a tissue expander after mastectomy.

  3. A Study To Assess A Change In Disease Activity And Adverse Events Of Intravenous Etentamig And Daratumumab (Etentamig+D) Compared To Daratumumab, Lenalidomide, And Dexamethasone (DRd) In Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible For Transplant - Mayo Clinic

    Participants in phase 2 will receive 1 of 3 doses of etentamig as intravenous (IV) infusions, combination with subcutaneous (SC) injections of daratumumab.

  4. A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy - Mayo Clinic

    A Phase 2 Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Safety and Efficacy of Lutikizumab (ABT-981) in Adult Subjects with ...

  5. Phase I Dose Escalation Study for BAY 1251152 in Patients With Advanced Cancer - Mayo Clinic

    About this study. Determine the safety, tolerability, pharmacokinetics, maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of BAY 1251152 in ...

  6. Trial of TRC105 and Sorafenib in Patients With HCC - Mayo Clinic

    Up to 21 patients will be treated in phase 2. Participation eligibility. Participant eligibility includes age, gender, type and stage of disease, and previous ...

  7. Virotherapy Clinical Trials - Mayo Clinic Research

    The purpose of this study is to determine the recommended Phase 2 dose (RP2D) of TBio-6517 when administered by direct injection into tumor(s) alone and when ...

  8. Another critical reason to prevent and control diabetes: It is a top cause of chronic kidney disease - Mayo Clinic News Network

    It can progress to end-stage kidney failure, which can be fatal without dialysis or a kidney transplant. Both type 1 and type 2 diabetes can lead to chronic ...

  9. Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumors - Mayo Clinic

    This Phase 1/2 study will enroll patients with various advanced solid tumors. Participation eligibility. Participant eligibility includes age, gender, type and ...

  10. Stem Cell Therapy Clinical Trials - Mayo Clinic Research

    The primary purpose of the phase II study is to estimate the progression-free survival rate at 2 years post-registration to see if treatment is efficacious ...