Search Results 291-300 of 37953 for Two-phase

1. Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors - Mayo Clinic

   Also, to establish for future clinical development the recommended Phase 2 dose (RP2D) of Q901 monotherapy when administered via IV infusion QW for 4 weeks and ...

2. Mayo Clinic Comprehensive Cancer Center to highlight key studies at ASCO 2024

   The impact of adjuvant endocrine therapy (AET) omission in estrogen receptor (ER)-low (1%-10%) early-stage breast cancer · Final results of a phase 2 study of ...

3. Neurology - Clinical trials - Mayo Clinic

   The purpose of this study is to determine the maximum tolerated dose (MTD) and/or the recommended Phase 2 dose (RP2D) of WSD0922-FU in subjects with ...

4. A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease - Mayo Clinic

   The START study is a multicenter randomized, double-blind, placebo-controlled Phase 2 study designed to evaluate the efficacy, safety, and tolerability of two ...

5. Anal fistula - Diagnosis and treatment - Mayo Clinic

   Fistulotomy may be done in two stages if a significant amount of sphincter ... LIFT is a two-stage treatment for more-complex or deep fistulas. LIFT ...

6. First-in-Human Study of KO-947 in Non-Hematological Malignancies - Mayo Clinic

   If an MTD cannot be identified, a recommended phase 2 dose (RP2D) will be determined. In addition, two tumor specific extension cohorts may be conducted to ...

7. Neoadjuvant Pembrolizumab - Mayo Clinic

   This multi-institutional, phase 2 clinical trial is studying two doses of pembrolizumab administered prior to surgery (neoadjuvant therapy) and 4 doses ...

8. Trastuzumab Emtansine in Treating Older Patients With Human Epidermal Growth Factor Receptor 2-Positive Stage I-III Breast Cancer - Mayo Clinic

   This phase II trial studies how well trastuzumab emtansine works in treating older patients with human epidermal growth factor receptor 2 (HER2)-positive stage ...

9. A Randomized Phase III Trial of Eribulin Compared to Standard Weekly Paclitaxel as First- or Second-Line Therapy for Locally Recurrent or Metastatic Breast Cancer - Mayo Clinic

   This is a two arm Phase III trial in first and second-line HER2 negative patients with locally recurrent or metastatic breast cancer. The primary endpoint ...

10. Takayasu's arteritis - Symptoms and causes - Mayo Clinic

    The signs and symptoms of Takayasu's arteritis often occur in two stages. ... Stage 2. During the second stage, inflammation causes arteries to narrow so ...