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  1. Polycystic Ovary Syndrome Clinical Trials - Mayo Clinic Research

    The investigators propose here to use both targeted and non-targeted metabolomic approach to identify pathways associated with metformin's effect on insulin ...

  2. Clinical Trials - Behavior of Valve Leaflets

    This is a prospective, interventional, multi-center trial to report the overall incidence of reduced leaflet motion identified by CT imaging in patients ...

  3. A Study to Compare the Effects of Liver Preservation for Transplant via Normothermic Machine Perfusion, versus Static Cold Storage - Mayo Clinic

    The purpose of this study is to compare the effects of normothermic machine profusion versus static cold storage for preventing preservation-related graft ...

  4. A Study to Investigate the Effectiveness and Safety of Fenfluramine Hydrochloride as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome - Mayo Clinic

    This is a two-part, multicenter, double-blind, parallel-group, placebo controlled study to evaluate the effect of ZX008 when used as adjunctive therapy for the ...

  5. A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease - Mayo Clinic

    The primary objective is to evaluate whether macitentan 10 mg reduces N-terminal pro-brain natriuretic peptide (NT-pro-BNP) as compared to placebo in these ...

  6. Non-Contact Point Of Care Device to Detect Signals During Sleep Studies - Mayo Clinic

    In Phase II of the study, the following aims are proposed to mature the prototype hardware into a production ready system, to finalize processing software and ...

  7. Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) - Mayo Clinic

    The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic, which may reduce bowel movement ...

  8. A Study to Evaluate the Effectiveness and Safety of PANZYGA in Pediatric Patients with Chronic Immune Thrombocytopenia (ITP) - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness and safety of PANZYGA in pediatric patients with chronic Immune Thrombocytopenia (ITP). Participation ...

  9. Healthy Immigrant Community: Mobilizing the Power of Social Networks - Mayo Clinic

    The objective of this study is to leverage existing social networks for health behavior change relevant to obesity and cardiovascular risk among immigrant ...

  10. A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) - Mayo Clinic

    This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic ...