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  1. A Study to Investigate the Effectiveness and Safety of Fenfluramine Hydrochloride as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome - Mayo Clinic

    This is a two-part, multicenter, double-blind, parallel-group, placebo controlled study to evaluate the effect of ZX008 when used as adjunctive therapy for the ...

  2. A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease - Mayo Clinic

    The primary objective is to evaluate whether macitentan 10 mg reduces N-terminal pro-brain natriuretic peptide (NT-pro-BNP) as compared to placebo in these ...

  3. Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction - Mayo Clinic

    Devices are to be programmed with zone cutoffs at 200 bpm and 250 bmp in order to mimic the programming settings for transvenous ICDs in the MADIT RIT study.

  4. Non-Contact Point Of Care Device to Detect Signals During Sleep Studies - Mayo Clinic

    In Phase II of the study, the following aims are proposed to mature the prototype hardware into a production ready system, to finalize processing software and ...

  5. Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) - Mayo Clinic

    The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic, which may reduce bowel movement ...

  6. Healthy Immigrant Community: Mobilizing the Power of Social Networks - Mayo Clinic

    The objective of this study is to leverage existing social networks for health behavior change relevant to obesity and cardiovascular risk among immigrant ...

  7. A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) - Mayo Clinic

    This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic ...

  8. Faculty - Department of Anesthesiology and Perioperative Medicine-Research - Mayo Clinic Research

    Review research biographies and published research from faculty members in the Department of Anesthesiology and Perioperative Medicine-Research at Mayo ...

  9. Cardiac Troponin Fragments in Peripartum Cardiomyopathy - Mayo Clinic

    We will also determine whether cTn fragment profile correlates with left ventricular recovery. Finally, we aim to establish a Bio bank in order to facilitate ...

  10. Thoracic Outlet Syndrome Clinical Trials - Mayo Clinic Research

    The purpose of this study is to assess the patient's quality of life following the paravertebral block(s) day post-op, 3-day post-op, 7-day post-op, and 2 weeks ...