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  1. A Study of Unesbulin Combined with Dacarbazine to Treat Advanced Leiomyosarcoma (LMS) - Mayo Clinic

    The primary purpose of this study is to determine the maximum tolerated dose (MTD) and overall safety profile of PTC596 in combination with dacarbazine for the ...

  2. Ixazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib - Mayo Clinic

    Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Participation eligibility. Participant eligibility ...

  3. A Study to Evaluate the Accuracy of the CapsoCam® Colon (CV-3) in Detecting Colonic Polyps Compared to Colonoscopy - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of CapsoCam® Colon (CV-3) endoscope system for the detection of colonic polyps. It is ...

  4. A Study To Compare The Safety And Efficacy Of Dysport® And Botox® In Adults With Upper Limb Spasticity - Mayo Clinic

    About this study. The purpose of this study is to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as ...

  5. Comparing Retreatment Of 177Lu-DOTATATE PRRT Versus Everolimus In Patients With Metastatic Unresectable Midgut Neuroendocrine Tumors, NET RETREAT Trial - Mayo Clinic

    About this study. The purpose of this study is tol compare the effect of retreatment with 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) to the ...

  6. A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC - Mayo Clinic

    This is a Phase I/II study designed to evaluate if experimental anti-TIGIT/anti-PD-1 bispecific antibody rilvegostomig (AZD2936) is safe, tolerable and ...

  8. Double Arm Pivotal Study to Evaluate the Neurolyser XR for the Treatment of Chronic Low Back Pain - Mayo Clinic

    The purpose of this study is to evaluate the Neurolyser XR as a non-invasive treatment of axial chronic low back pain; to investigate the effectiveness of HIFU, ...

  9. CJNJ-67652000 And Prednisone For The Treatment Of Men With Metastatic Castration-Resistant Prostate Cancer And SPOP Gene Mutations - Mayo Clinic

    Giving CJNJ-67652000 and prednisone may kill more tumor cells in patients with metastatic prostate cancer than giving these drugs alone. Participation ...

  10. Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...