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1. A Study to Evaluate the Safety, Tolerability and Metabolism of BIIB105 in Subjects with Amyotrophic Lateral Sclerosis - Mayo Clinic

   The primary objective is to evaluate the safety and tolerability of BIIB105 in participants with amyotrophic lateral sclerosis (ALS) or poly-CAG expansion ( ...

2. A Study Of THE-630 In Patients With Advanced Gastrointestinal Stromal Tumors (GIST) - Mayo Clinic

   The purpose of this study is to assess the safety, effectiveness, and pharmacokinetics of THE-630 in participants with advanced gastrointestinal stromal tumors ...

3. A Study Of Ripretinib Vs Sunitinib In Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib - Mayo Clinic

   The purpose of this study is to compare the objective response rate (ORR) by IRR of ripretinib vs sunitinib using modified Response Evaluation Criteria in Solid ...

4. A Study Of The Efficacy And Safety Of Belimumab Compared To Placebo In Adults With Systemic Sclerosis Associated Interstitial Lung Disease - Mayo Clinic

   The purpose of this study is to determine the effectiveness and safety of belimumab compared to placebo in adults with systemic sclerosis (SSc) associated ...

5. A Study Of Glofitamab And Lenalidomide In People With Mantle Cell Lymphoma - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

6. Study Of Tirabrutinib (ONO-4059) In Patients With Primary Central Nervous System Lymphoma (PROSPECT Study) - Mayo Clinic

   About this study. The purose of this study is to evaluate the effiectiveness, safety, and pharmacokinetics of tirabrutinib monotherapy in patients with ...

7. Testing The Addition Of An Anti-cancer Drug, ASTX727, To Chemotherapy (Paclitaxel) And Immunotherapy (Pembrolizumab) For Metastatic Triple-Negative Breast Cancer - Mayo Clinic

   The purpose of this study is to test the safety, side effects, and best dose of ASTX727 when given together with paclitaxel and pembrolizumab in patients with ...

8. Zephyrus II: Effectiveness And Safety Study Of Pamrevlumab In Participants With Idiopathic Pulmonary Fibrosis (IPF) - Mayo Clinic

   The purpose of this trial is to evaluate the effectiveness and safety of pamrevlumab in subjects with idiopathic pulmonary fibrosis (IPF). Subjects who were ...

9. Evaluation Of C-Scan Capsule In Identifying Subjects With Elevated Risk Of Colon Polyps - Mayo Clinic

   Subjects will be asked to ingest contrast agent fluid and fiber pills starting 48 hours before capsule swallowing, up to capsule natural excretion. Standard ...

10. A Study Of CTX-009 In Combination With Paclitaxel In Adult Patients With Unresectable Advanced, Metastatic Or Recurrent Biliary Tract Cancers (COMPANION-002) - Mayo Clinic

    paclitaxel alone in patients with biliary tract cancers (BTC) who have received one systemic therapy for advanced disease, as measured by Overall Response Rate ...