Search Results 201-210 of 16768 for alt

  1. Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumors - Mayo Clinic

    Aspartate aminotransferase/alanine aminotransferase (AST/ALT) ≤ 3 upper limit of normal (ULN). In cases with liver involvement ALT/ AST ≤ 5× ULN. Total ...

  2. Phase I Study Of BL0020, A Novel Anti-tumor Drug, In Adult Subjects With Advanced Solid Tumors - Mayo Clinic

    * Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) \> 3×ULN without liver metastases or primary liver cancer. AST or ALT \> 5×ULN if the ...

  3. TheraSphere With and Without Durvalumab and Tremelimumab for HCC - Mayo Clinic

    ... ALT should be ≤3xULN and for treated patients, antiviral treatment (per local standard of care) should be stopped for a minimum of 14 days prior to study ...

  4. A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT - Mayo Clinic

    - Note: For the purpose of this study, the ULN for SGPT (ALT) has been set to the value of 45 U/L. - Central nervous system function defined as: - Patients ...

  5. CATALINA-2: A Clinical Study Of TORL-1-23 In Platinum-resistant Ovarian Cancer.

    ... ALT (SGPT): ≤3 X ULN (participants with active liver metastases who have ALT/AST ≤5 X ULN may be enrolled) * Albumin: ≥2.5 g/dL * ECG: 12-Lead ECG with ...

  6. Study of INCB053914 in Subjects With Advanced Malignancies - Mayo Clinic

    AST or ALT > 1.5 × ULN;; Creatinine clearance < 50 mL/min (< 30 mL/min for MM) based on Cockroft-Gault formula or 24-hour urine analysis. Part 2 and Part 4 ...

  7. Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma - Mayo Clinic

    ... (ALT) =< 3 x ULN (within 28 days prior to step 1 registration) - No other prior malignancy is allowed except for the following: adequately treated basal cell ...

  8. Alisertib in Treating Patients With Myelofibrosis or Relapsed or Refractory Acute Megakaryoblastic Leukemia - Mayo Clinic

    AMKL PATIENTS: Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ≤ 2.5 x ULN. AMKL PATIENTS: Creatinine < 1.5 x ULN or calculated creatinine ...

  9. Study Of HPN536 In Patients With Advanced Cancers Associated With Mesothelin Expression - Mayo Clinic

    Aspartate and alanine transaminase (AST and ALT) ≤ 2.5 x ULN or AST/ALT ≤ 5 x ULN for patients with liver metastases. Serum albumin ≥ 30 mg/mL. Exclusion ...

  10. Safety and Efficacy of Selonsertib, GS-0976, GS-9674, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) - Mayo Clinic

    Alanine aminotransferase (ALT) < 5 x Upper Limits of Normal (ULN); Platelet count ≥ 125,000/μL. Exclusion Criteria: Prior history of decompensated liver ...