Search Results 11-20 of 14794 for Proto-oncogene

1. Phase III Study Of Datopotamab Deruxtecan Versus Docetaxel In Previously Treated TROP2-positive Advanced Or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations - Mayo Clinic

   ... proto-oncogene 1 (ROS1) genomic alterations. * Has no known tumour genomic alterations in neurotrophic tyrosine receptor kinase (NTRK), proto-oncogene B-raf ...

2. Cancer-Causing Gene Alone Doesn't Trigger Pancreatic Cancer, Mayo-led Study Finds

   The study, published in the Sept. 10 issue of Cancer Cell, overturns the current belief that a mutation in the KRAS oncogene is enough to initiate pancreatic ...

3. Epigenetic Etiology of Human Disease: Keith D. Robertson

   This heat map (visualization tool) illustrates changes in epigenetic marks across the genome from a panel of primary renal cell cancers. Overview. This ...

4. Drug Combo Shuts Down Stem Cells, Tumor Growth in Lung Cancer - Mayo Clinic News Network

   Found PKCiota activates a second oncogene, known as SOX2, to stimulate cancer stem cell growth in lung squamous cell carcinoma. Dr. Fields says the current ...

5. ABT-888 With Cyclophosphamide in Refractory BRCA-Positive Ovarian, Primary Peritoneal or Ovarian High-Grade Serous Carcinoma, Fallopian Tube Cancer, Triple-Negative Breast Cancer, and Low-Grade Non-Hodgkin's Lymphoma - Mayo Clinic

   ... protooncogenes(c-myc, c-fos and c-myb) in ... These oncogenes are critically regulated during ... Thus, the high level of the expression of these oncogenes may not ...

6. Uncovering Signaling Pathways That Regulate Invasion and Metastasis of Cancer Cells - Tumor Development, Immunology and Progression Laboratory - Mayo Clinic Research

   While PKD1 mediates cell proliferation and also acts as a suppressor of breast tumor cell invasion, PKD3, when expressed, mediates all oncogenic functions.

7. Cellular Responses to DNA Damage Induced by Topoisomerase Poisons - Anticancer Drug Action Laboratory - Mayo Clinic Research

   Dr. Kaufmann and his team in the Anticancer Drug Action Lab at Mayo Clinic are studying cellular responses to DNA damage induced by topoisomerase poisons.

8. Publications - Debra A. Bell, M.D. - Mayo Clinic

   Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy. Cancer Res. 1993 Apr 1; 53(7):1489-92. View PubMed; Goff BA, Muntz ...

9. Non-Hodgkin's Lymphoma Clinical Trials - Mayo Clinic Research

   Duvelisib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as CC-486, cyclophosphamide, ...

10. Mayo Clinic uncovers hidden driver fueling aggressive prostate cancer

    Treatments such as chemotherapy, hormone therapy and immunotherapy have had limited success against advanced prostate cancer due to the tumor's ability to ...