Search Results 11-20 of 16545 for Proto-oncogene

  1. Oncogenic osteomalacia, pearls from an elusive tumor: A case from the endocrine teaching clinics

    Natalia Genere, M.D., and Robert D. Tiegs, M.D., discuss the care plan for a woman who presented with multiple, nontraumatic fractures discovered during a ...

  2. Mayo Clinic Researchers Identify Gene that Pushes Normal Pancreas Cells to Change Shape, a Key Step to Cancer Development

    However, the presence of oncogenic signaling (Kras mutations, EGF-R) can push these duct cells to develop lesions that are at risk for tumor development. To ...

  3. Drug Combo Shuts Down Stem Cells, Tumor Growth in Lung Cancer - Mayo Clinic News Network

    Found PKCiota activates a second oncogene, known as SOX2, to stimulate cancer stem cell growth in lung squamous cell carcinoma. Dr. Fields says the current ...

  4. Ongoing Basic Science Research Studies - Hepatobiliary Cancer Laboratory - Mayo Clinic Research

    The Oncogenic Role of Hepatitis B Virus Integration Into the Host Genome in Liver Cancer. The Hepatobiliary Cancer Lab is identifying the key functions and ...

  5. A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer - Mayo Clinic

    (ALK), B-Raf proto-oncogene (BRAF) or ROS proto-oncogene 1 (ROS1) mutations who have not received appropriate therapies targeting these mutations and ...

  6. Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer

    The neu (c-erbB-2) proto-oncogene encodes a tyrosine kinase receptor that is overexpressed in 20 to 30% of human breast tumors. Herein, cyclin D1 protein ...

  7. Uncovering the Signaling Events Underlying the Development and Progression of Pancreatic Cancer - Tumor Development, Immunology and Progression Laboratory - Mayo Clinic Research

    The lab team has confirmed activation of this signaling pathway by oncogenic KRas as a key event driving the development of pancreatic cancer. The lab's ...

  8. Molecule Thought Cancer Foe Actually Helps Thyroid Tumors Grow - Mayo Clinic News Network

    A different member of the cyclin family — cyclin A2 — is a well-known oncogene, but, before this study, no one had shown that cyclin A1 does the same thing ...

  9. Effect of TTFields (150 kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-10 Brain Metastases Following Radiosurgery (METIS) - Mayo Clinic

    ... proto-oncogene, and proto-oncogene B-RAF. Patients who have a single, operable brain metastasis. Patients with significant edema leading to risk of brain ...

  10. Overview - Genetic Screening and Engineering Core - Mayo Clinic Research Core Facilities

    Cancer biology. CRISPR-based approaches help investigate tumor suppressors, oncogenes and drug resistance mechanisms. Cell therapy. Precision gene editing ...