Search Results 1961-1970 of 16610 for Maximum
When p300 is inhibited, this drives synthetic lethality leading to apoptosis/cell death. This study will determine the maximum tolerated dose (MTD) and/or ...
The purpose of this study is to evaluate the effects of GBT440 on the body and oxygen saturation levels , assessed at rest and at maximum exercise under ...
however, for these patients the maximum permitted daily dose of pitolisant is 17.8 mg. 17. Is a known CYP2D6 poor metabolizer (PM). 18. Has abnormal ...
The purpose of phase 1 of this trial is to determine the maximum tolerated dose of temozolomide followed by selinexor in recurrent glioblastoma patients as ...
The primary objectives are to determine the maximum tolerated dose (MTD) or highest protocol-defined dose (HPDD); in the absence of exceeding the MTD of ...
The purpose of this study is to determine the maximum tolerated dose (MTD) and schedule and/or a recommended Phase 2 dose (RP2D) and schedule of KTX-1001 ...
... determine the maximum tolerated dose (MTD), identify a recommended phase 2 dose (RP2D) and preferred schedule, and assess preliminary anti-tumor activity.
... maximum) over a period of 12 months * Visit the clinic three times for the first week of cycle one, then once a week for the remaining 7 weeks of cycle 1 ...
... maximum tolerated dose (part 1). Additional end points included pharmacokinetics/pharmacodynamics and preliminary efficacy. Reported herein are results from ...
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