Search Results 181-190 of 38822 for Two-phase

1. Nonalcoholic Steatohepatitis Clinical Trials - Mayo Clinic Research

   ... stage 2 or 3. The primary objective for PART 2 of this study is to ... It will consist of 2 phases: - Randomized Double-Blind Phase - Open Label Phase (optional).

2. LEAP 2 Chronic EFS - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

3. A Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Effectiveness of Isatuximab in Patients Awaiting Kidney Transplantation - Mayo Clinic

   The primary purpose of this study in Phase 2 is to evaluate the effectiveness of isatuximab in desensitization of patients awaiting kidney transplantation.

4. Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors - Mayo Clinic

   This study will also learn more about how the combination of these two investigational drugs may work for patients with certain cancers (specifically metastatic ...

5. Kidney transplant - Mayo Clinic

   Polycystic kidney disease. People with end-stage renal disease need to have a kidney transplant or dialysis to stay alive. Dialysis removes waste from the ...

6. Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral CDAi in Patients With MDS - Mayo Clinic

   This 2-stage, open-label study will evaluate safety and pharmacokinetics of ASTX727, as well as determine the dose for the study's second stage. In the second ...

7. Study to Evaluate the Efficacy and Safety of CUDC-907 in Patients With RR DLBCL, Including Patients With MYC Alterations - Mayo Clinic

   This is a Phase 2, open-label, multicenter trial designed to evaluate the efficacy and safety of CUDC-907 in subjects 18 years and older with Relapsed ...

8. PAC203: A Randomized, Controlled Phase 3 Study of Pacritinib Versus Physician’s Choice in Patients with Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post Essential Thrombocythemia Myelofibrosis with Severe Thrombocytopenia (Platelet Counts <50,000/μL) (PACIFICA) - Mayo Clinic

   PMF, PPV-MF, or PET-MF (as defined by Tefferi and Vardiman 2008). · Platelet count of <50,000/μL at Screening (Day -35 to Day -3) (based on two measurements ...

9. Phase 1 clinical trial testing gene therapy treatment for knee osteoarthritis

   Dr. Evans notes that successful phase 2 and 3 trials will be necessary before the treatment can achieve Food and Drug Administration (FDA) approval. "If ...

10. A Phase 1/2a Dose-Finding Study of PT-112 in Patients With Relapsed or Refractory Multiple Myeloma - Mayo Clinic

    This is designed as a two-part study. In the first part of the study, cohorts of three patients (expanded to six patients in the event of a dose-limiting ...