Search Results 1841-1850 of 18785 for Activation

1. A Study to Investigate the Safety and Tolerability of REGN1979 in Patients With CD20+ B-Cell Malignancies - Mayo Clinic

   Activated B-cell type; Note: DLBCL includes both de novo DLBCL and transformed DLBCL arising from indolent lymphoma/CLL. Primary mediastinal (thymic) large B ...

2. A Phase 1/2, First-in-Human, Open Label, Dose Escalation Study Of A CSP Targeting Functional Antibody in Solid Tumors - Mayo Clinic

   thromboplastin time (PTT) or activated partial thromboplastin time (APTT) <1.25 x ULN (therapeutic anticoagulation. Note: Anti-coagulation therapy is ...

3. Clinical trials - Oncology (Medical)

   MC1733, Phase I Trial of Intratumoral Administration of a Measles Virus Derivative Expressing the Helicobacter pylori Neutrophil-activating Protein (NAP) ...

4. Oral AMXT 1501 Dicaprate in Combination With IV DFMO - Mayo Clinic

   Activated partial thromboplastin time/ partial thromboplastin time (aPTT/PTT) ≤ 1.5 × ULN;; Aspartate aminotransferase (AST) and alanine aminotransferase ...

5. A Study to Evaluate DS-8201a Combined with Olaparib in HER2-Expressing Cancers with Expansion in Endometrial Cancer Patients Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Endometrial Cancer - Mayo Clinic

   International Normalized ratio ≤ 1.5 × ULN (INR)/Prothrombin time (PT) and activated partial thromboplastin time (aPTT);; Creatinine ≤ 1.5 × institutional ...

6. A Study to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors - Mayo Clinic

   Activated partial thromboplastin time (aPTT) ≤1.5 × ULN unless participant is receiving anticoagulant therapy as long as PT or aPTT is within therapeutic ...

7. Oncology (Medical) - Clinical trials

   We present here a CAR design that allows PD-1 to recognize PD-L1 on the tumor; however, the intracellular CAR design is one that results in T cell activation as ...

8. Precision medicine for breast cancer - Care at Mayo Clinic

   CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nature Communications. 2017; doi:10.1038/ncomms13923. Luo K, et al. A ...

9. MAYO CLINIC HEALTH LETTER

   This squeezes blood into the heart's two lower chambers (ventricles). After activating the atria, the electri- cal signals converge at another group of ...

10. Clinical trials - Oncology (Medical)

    We present here a CAR design that allows PD-1 to recognize PD-L1 on the tumor; however, the intracellular CAR design is one that results in T cell activation as ...