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  1. Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma (KarMMa) - Mayo Clinic

    A leukapheresis procedure will be performed to manufacture bb2121 chimeric antigen receptor (CAR) modified T cells. Prior to bb2121 infusion subjects will ...

  2. A Study to Compare Acoustic and Electric Reflex Thresholds - Mayo Clinic

    The purpose of this study is to analyze immittance patterns, both acoustically and electrically, for patients with either cochlear implantation or auditory ...

  3. MEVOKED and PHQ9 Data - Clinical Trials

    This study will obtain additional information on participants – in particular PHQ9 depression scores and medication use during their enrollment in the MEVOKED ...

  4. A Study to Evaluate the Activity of 2 Dose Levels of Imetelstat in Participants with Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated with Janus Kinase (JAK) Inhibitor - Mayo Clinic

    The purpose of this study is to evaluate the percentage of spleen (largest lymph organ in the body) response and symptom response of 2 dose regimens of ...

  5. Topical SGX301 (Synthetic Hypericin) For The Treatment Of Cutaneous T-Cell Lymphoma (Mycosis Fungoides) - Mayo Clinic

    FLASH [Fluorescent Light Activated Synthetic Hypericin] Clinical Study: Topical SGX301 (Synthetic Hypericin) For The Treatment Of Cutaneous T-Cell Lymphoma ( ...

  6. Understanding the Resistance to Enzalutamide in Patients with Castrate Resistant Metastatic Prostate Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. A Study Comparing a Protective Ventilation Plan with Higher versus Lower Positive End Expiratory Pressure During General Anesthesia in Surgery for Obese Patients - Mayo Clinic

    About this study. The purpose of this study is to compare a ventilation strategy using higher levels of positive end expiratory pressure and recruitment ...

  8. A Registry of High Resolution Optical Imaging of the Esophagus Using the NvisionVLE™ Imaging System - Mayo Clinic

    About this study. The purpose of this registry of patients undergoing EGD or endoscopy is to provide a collection of patient NvisionVLE™ (volumetric laser ...

  9. Tumor Infiltrating Lymphocytes Biobank - Clinical Trials

    The purpose of this repository is to provide clinical samples to support basic science and translational research efforts to improve TIL therapy. The process of ...

  10. Phase 1/2 Study of AG-221 in Subjects With Advanced Hematologic Malignancies With an IDH2 Mutation - Mayo Clinic

    About this study. Study AG221-C-001 is a Phase 1/2, multicenter, open-label, dose-escalation, safety, PK/PD, and clinical activity evaluation of orally ...