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  1. Dupilumab Treatment on Sinonasal Respiratory Symptoms and Sense of Smell in Ethnically Diverse Patients with Chronic Rhinosinusitis and Nasal Polyps - Mayo Clinic

    The purpose of this study is to to identify pathways by which dupilumab may “normalize” the immune response in patients with Chronic Rhinosinusitis and Nasal ...

  2. AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis - Mayo Clinic

    This study is a placebo-controlled Phase I study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide ( ...

  3. A Study to Develop a Program for those Living Alone with Mild Cognitive Impairment - Mayo Clinic

    The purpose of this study is to develop a program for individuals living alone with mild cognitive impairment (MCI). Participation eligibility. Participant ...

  4. A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  5. A Study of Previously Untreated Patients (PUPs) with Congenital Hemophilia - Mayo Clinic

    The purpose of this study is to determine the percentage of subjects with confirmed inhibitors (per CDC laboratory criteria; >0.5 Nijmegen Bethesda Units for ...

  6. Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases - Mayo Clinic

    About this study. The purpose of this study is to create a repository for cerebellar ataxia and nucleotide repeat diseases in order to fully investigate the ...

  7. A Study to Evaluate the Endorotor® Resection In Refractory Barrett's Dysplasia Patients - Mayo Clinic

    About this study. The aim of the clinical trial is evaluate the EndoRotor®'s ability to completely remove areas of Barrett's metaplasia considered ...

  8. Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2) - Mayo Clinic

    About this study. This is a multicenter, randomized, double-blind, parallel group, chronic-dosing (24 weeks), placebo-controlled study to assess the ...

  9. CYP2C19 Genotype Predictor of Gastric Acid Suppression - Mayo Clinic

    About this study. If CYP2C19 genotype can predict the efficacy of healing erosive esophagitis and gastric acid secretion in patients taking once a day ...

  10. Analysis of the Mid-Upper Gastrointestinal Tract in Adults - Mayo Clinic

    Bacteria are essential for human life; they are needed to digest food, break down certain vitamins and form a barrier against disease-causing bacteria. We are ...