Search Results 1721-1730 of 18798 for Activation

  1. Clinical trials - Oncology (Medical)

    We present here a CAR design that allows PD-1 to recognize PD-L1 on the tumor; however, the intracellular CAR design is one that results in T cell activation as ...

  2. GATE1: A Multicenter Phase II Study Of Pirtobrutinib, Rituximab And Venetoclax Combination Therapy For Patients With Previously Untreated Mantle Cell Lymphoma - Mayo Clinic

    * Activated partial thromboplastin time (aPTT) or partial thromboplastin time (PTT) ≤ 1.5 × ULN * Total bilirubin ≤ 1.5 × ULN, or ≤ 3 × ULN if there is ...

  3. A Study To Test The Addition Of The Drug Cabozantinib To Chemotherapy In Patients With Newly Diagnosed Osteosarcoma - Mayo Clinic

    Cabozantinib is in a class of medications called kinase inhibitors which block protein signals affecting new blood vessel formation and the ability to activate ...

  4. A Study to Evaluate Niraparib and TSR-042 in Patients with Germline or Somatic BRCA1/2 and PALB2-related Pancreatic Cancer - Mayo Clinic

    Activated partial thromboplastin time (aPTT) ≤1.5× ULN unless patient is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range ...

  5. A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme - Mayo Clinic

    Activated partial thromboplastin time (aPTT) ≤ 1.5 × ULN. 13. Women of childbearing potential must agree to practice a highly effective method of

  6. Publications - Amye J. Tevaarwerk, M.D. - Mayo Clinic

    Paclitaxel Induces Micronucleation and Activates Pro-Inflammatory cGAS-STING Signaling in Triple-Negative Breast Cancer. Mol Cancer Ther. 2021 Dec; 20 (12): ...

  7. Publications - Elie Naddaf, M.D. - Mayo Clinic

    NLRP3 Inflammasome Activation and Altered Mitophagy Are Key Pathways in Inclusion Body Myositis. J Cachexia Sarcopenia Muscle. 2025 Feb; 16 (1):e13672. View ...

  8. Publications - Chia-Chun Chiang, M.D. - Mayo Clinic

    Is Stroke Code Activation for “Stroke Mimics” Decreasing with Stroke Center Certification Education. International Journal of Stroke. 2019 Jun. Hirschauer ...

  9. Obecabtagene autoleucel (intravenous route) - Side effects & uses - Mayo Clinic

    This medicine may cause a severe inflammatory condition that could be life-threatening, including hemophagocytic lymphohistiocytosis/macrophage activation ...

  10. Publications - Zhaohui Jin, M.D. - Mayo Clinic

    ... activated bad kinase. J Biol Chem. 2005 Apr 22; 280 (16):16045-52 Epub 2005 Feb 10. View PubMed; Jin Z, Gao F, Flagg T, Deng X. Tobacco-specific nitrosamine 4 ...