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  1. Safety And Potential Bioactivity Of CLBS16 In Patients With Coronary Microvascular Dysfunction And Without Obstructive Coronary Artery Disease - Mayo Clinic

    About this study. This clinical trial will explore the safety and effect of GCSF-mobilized autologous ex vivo selected CD34 cells for the treatment of CMD ...

  2. A Phase 1 Study Evaluating The Safety, PK, And Clinical Effects Of PT-112 In Subjects With Advanced Solid Tumors

    The purpose of this study is to determine the maximum tolerated dose, and evaluate its safety, tolerability, preliminary clinical effects, and drug/body ...

  3. A Study Of Abemaciclib (LY2835219) In Women With HR+, HER2+ Locally Advanced Or Metastatic Breast Cancer - Mayo Clinic

    About this study. The purpose of this study is to evaluate the effectiveness of abemaciclib plus trastuzumab with or without fulvestrant or chemotherapy in ...

  4. A Phase I, Multi-Center, Open Label, Dose De-escalation And Expansion Study Of Gemcitabine And Cisplatin With AG120 Or Pemigatinib For Advanced Cholangiocarcinoma - Mayo Clinic

    Ivosidenib and pemigatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving gemcitabine and cisplatin with ...

  5. Diuretics Alone Vs. Aortix Endovascular Device For Acute Heart Failure - Mayo Clinic

    Eligible ADHF patients with diuretic resistance (irrespective of ejection fraction) will be enrolled and randomized 1:1 to either the Aortix system or standard ...

  6. Efficacy And Safety Of Treatment With Alpelisib Plus Endocrine Therapy In Patients With HR+, HER2-negative ABC, With PIK3CA Mutations, Whose Disease Has Progressed On Or After CDK 4/6 Treatment With An Aromatase Inhibitor (AI) Or Fulvestrant - Mayo Clinic

    Efficacy And Safety Of Treatment With Alpelisib Plus Endocrine Therapy In Patients With HR+, HER2-negative ABC, With PIK3CA Mutations, Whose Disease Has ...

  7. A Study Of The Effectiveness And Safety Of CTL019 In Adult Patients With Diffuse Large B-Cell Lymphoma - Mayo Clinic

    The purpose of this study is to determine the efficacy and safety of CTL019 in adult patients with relapsed or resistant diffuse large B-cell lymphoma.

  8. A Study to Evaluate Patient Experience Comparing Tonic vs. Burst Spinal Card Stimulation for Chronic Pain - Mayo Clinic

    About this study. The purpose of this study is to evaluate if subjects who have already experienced tonic spinal cord stimulation would have a better pain ...

  9. Phase Ib, Dose Escalation Study Of Oral LDE225 In Combination With BKM120 In Patients With Advanced Solid Tumors - Mayo Clinic

    This study will also learn more about how the combination of these two investigational drugs may work for patients with certain cancers (specifically metastatic ...

  10. A Study Of 9-ING-41 In Patients With Advanced Cancers - Mayo Clinic

    Malignancy for which there is no standard therapy that improves survival by at least 3 months. Has evaluable tumor(s) by standard radiological and/or laboratory ...