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  1. A Dose Escalation Study Of Amivantamab In Participants With Advanced Non-Small Cell Lung Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  2. A Study Of CIN-107 In Adults With Primary Aldosteronism - Mayo Clinic

    The purpose of this study is to evaluate the change from baseline in systolic blood pressure (SBP) by automated office blood pressure monitoring (AOBPM), with ...

  3. Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer - Mayo Clinic

    Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. It is not yet known whether giving combination ...

  4. Testing The Addition Of Paclitaxel Administered Into The Abdominal Cavity Combined With Chemotherapy For Patients With Gastric Cancer Spread To The Abdominal Cavity - Mayo Clinic

    This study is being done to answer the following questions: Can we lower the chance of your gastric cancer from growing or spreading by administering paclitaxel ...

  5. A Trial To Evaluate The Effectiveness, Safety, Tolerability And Pharmacokinetics Of HZN-825 In Patients With Diffuse Cutaneous Systemic Sclerosis - Mayo Clinic

    The primary purpose of this study is to demonstrate the effectiveness of 1 or 2 dose levels of HZN-825 versus placebo in subjects with diffuse cutaneous ...

  6. (VOYAGER) Study Of Avapritinib Vs Regorafenib In Patients With Locally Advanced Unresectable Or Metastatic GIST - Mayo Clinic

    About this study. This is an open-label, randomized, Phase 3 study in patients with locally advanced unresectable or metastatic GIST (advanced GIST) of ...

  7. Trial Of TRC105 And Sorafenib In Patients With HCC - Mayo Clinic

    About this study. The purpose of the phase 1b portion is to evaluate safety and tolerability and determine a recommended phase 2 dose for TRC105 when added ...

  8. Namilumab In Subjects With Chronic Pulmonary Sarcoidosis - Mayo Clinic

    Sarcoidosis is a multi-organ autoimmune disease characterized by non-necrotizing granulomas believed to be formed from an exaggerated immune response to ...

  9. A Pilot Study to Evaluate the Contribution of the Saphenous Nerve in Ankle Pain of Patients With Degenerative Joint Disease of the Ankle - Mayo Clinic

    To assess the pain scores before and after saphenous nerve block placement in patients with degenerative joint disease of the ankle. Participation eligibility.

  10. A Study Comparing Nicotine Lozenges to Tobacco-Free Snuff for Reducing the Use of Smokeless Tobacco - Mayo Clinic

    The purpose of this study is to to develop a Smokeless Tobacco (ST) reduction intervention among ST users not interested in quitting tobacco. The first step is ...