Search Results 141-150 of 16784 for alt

1. A Study of Zetomipzomib (KZR-616) in Patients With Autoimmune Hepatitis (PORTOLA) - Mayo Clinic

   * Screening ALT values that are 1.25 to 10 times the upper limit of the normal range (ULN) * Liver biopsy results with Ishak score (modified HAI) ≥5/18 ...

2. Pasireotide LAR in Severe Polycystic Liver Disease - Mayo Clinic

   ALT and AST ≤ 2 x ULN. Estimated glomerular filtration rate (eGFR) >30 ml/min/m2; Serum amylase and lipase ≤ 1.5 x ULN; Alkaline phosphatase ≤ 2.5 x ULN ...

3. Study Evaluating the Safety, Tolerability, and Effectiveness of EDP-305 in Subjects with Nonalcoholic Steatohepatitis (NASH) - Mayo Clinic

   Histologic evidence on a historical liver biopsy within 24 months of Screening consistent with NASH with fibrosis (no cirrhosis), and elevated ALT at Screening;.

4. A Global, Randomized, Placebo-controlled Phase 3 Study Of Fruquintinib In Patients With Refractory Metastatic Colorectal Cancer - Mayo Clinic

   ... ALT are eligible. Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) > 2.5 × ULN in patients without hepatic metastases; ALT or AST >5 × ULN ...

5. Study To Evaluate The Efficacy And Safety Of Elafibranor In Patients With Primary Biliary Cholangitis (PBC) And Inadequate Response To Ursodeoxycholic Acid - Mayo Clinic

   'AIH-PBC overlap syndrome' is based upon fulfilment of the Paris criteria (Chazouilléres 1998)for both AIH (ALT ≥5x ULN; IgG ≥2x ULN or smooth muscle ...

6. Trial of Anakinra (Plus Zinc), or Prednisone in Patients With Severe Alcoholic Hepatitis - Mayo Clinic

   ... ALT ratio < 1.5), antinuclear antibody > 1:160 or SMA > 1:80, a standard of care liver biopsy may be performed during current hospital admission to confirm ...

7. Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair - Mayo Clinic

   Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x upper limit of normal (ULN); Thyroid-stimulating hormone (TSH) within normal limits ...

8. Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma - Mayo Clinic

   ... ALT < 5 times ULN for age). Shortening fraction of >= 27%; or; Ejection fraction of >= 50%. Patients must have a normal blood sugar level for age to ...

9. Combination Therapy Of Pegylated Interferon Alfa-2a And Tenofovir Versus Tenofovir Monotherapy In Chronic Hepatitis B - Mayo Clinic

   Serum ALT >450 U/L for males and >300 U/L for females (participants are eligible for re-screening if ALT levels fall to the range of eligibility). Treatment ...

10. A Study Using Momelotinib in Transfusion-Dependent Adults with Primary Myelofibrosis, Post-Polycythemia Vera or Post-Essential Thrombocythemia Myelofibrosis - Mayo Clinic

    Aspartate aminotransferase (AST/SGOT) and alanine aminotransferase (ALT/SGPT) ≤ 3 x upper limit of normal (ULN) or AST or ALT ≤ 5 x ULN if liver is involved ...