Search Results 1421-1430 of 18700 for Activation

1. VX15/2503 in Combination With Avelumab in Advanced Non-small Cell Lung Cancer - Mayo Clinic

   Tumors lack activating epidermal growth factor receptor (EGFR) mutations or ALK rearrangement (no EGFR or ALK testing is required if a subject has a KRAS ...

2. Drug Combo Shuts Down Stem Cells, Tumor Growth in Lung Cancer - Mayo Clinic News Network

   Found PKCiota activates a second oncogene, known as SOX2, to stimulate cancer stem cell growth in lung squamous cell carcinoma. Dr. Fields says the current ...

3. Parkinson's Disease Clinical Trials - Mayo Clinic Research

   This study is investigating the usefulness of using functional magnetic resonance imaging (fMRI) to monitor brain activation during deep brain stimulation for ...

4. Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinoma - Mayo Clinic

   Coagulation: International Normalized Ratio (INR) < 1.5 times normal, activated Partial Thromboplastin Time (aPTT) < 1.5 times normal. Patients receiving ...

5. A Study to Evaluate the Safety and Effectiveness of Capivasertib + Fulvestrant Versus Placebo + Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Breast Cancer - Mayo Clinic

   AKT pathway activation is implicated in endocrine-therapy resistance. Data on the efficacy and safety of the AKT inhibitor capivasertib, as an addition to ...

6. Progressive MS: Innovative tools for diagnosis and care - Mayo Clinic

   On a research basis, Mayo Clinic uses microglial PET scans to identify activated microglia, an important source of oxidated damage in MS. Serum and ...

7. Estrogen receptor mRNA directed therapy for triple negative breast cancer

   Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex ...

8. A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP) - Mayo Clinic

   ... activation of the vestibulo-ocular reflex (at later stages, the vestibulo-ocular reflex may be lost, or the maneuver prevented by nuchal rigidity), OR slow ...

9. Rajiv K. K. Pruthi, M.B.B.S. - Mayo Clinic Faculty Profiles

   continuous infusion of recombinant activated factor VII in hemophilia patients with inhibitors undergoing major surgery. The trial demonstrated that ...

10. A Clinical Study To Investigate The Efficacy And Safety Of An Investigational Combination Therapy With BNT324 And BNT327 In Patients With Advanced Lung Cancer - Mayo Clinic

    Have documented absence of tumor activating, targetable EGFR mutations or ALK gene rearrangements. Have received at least one line of prior therapy for ...