Search Results 1291-1300 of 21940 for Inhibition

1. An Early Access Program (EAP) for Avapritinib in Patients with Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor - Mayo Clinic

   Patient requires therapy with a concomitant medication that is a strong inhibitor or strong inducer of cytochrome P450 (CYP) 3A4;; Patient has had a major ...

2. Pancreatic Enucleation Clinical Trials - Mayo Clinic Research

   Olaparib is an inhibitor of PARP, an enzyme that helps repair ... PARP inhibitors are a type of targeted therapy. Pancreatic Surgery Database ...

3. Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases - Mayo Clinic

   - Planned administration of cytotoxic chemotherapy or tyrosine/multi-kinase inhibitors within the 3 days prior to, the day of, or within 3 days after the ...

4. Dendritic Cell Therapy After Cryosurgery in Combination With Pembrolizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Remove by Surgery - Mayo Clinic

   Failure to recover from prior side effects of immune checkpoint inhibitor therapy to ≤ Grade 1. NOTE: Patients will not be excluded for adrenal ...

5. A Study of the Safety and Effectiveness of Abicipar Pegol in Patients With Neovascular Age-related Macular Degeneration - Mayo Clinic

   Treatment with systemic anti-VEGF medication (e.g., bevacizumab, ziv-aflibercept) or VEGF-receptor inhibitor (e.g., sunitinib, sorafenib, pazopanib) within ...

6. Brain Tumor Stem Cell Research Lab - Patents

   Use of AGX/UAP inhibitors to inhibit flux through the hexosamine biosynthetic pathway, Pending. Sagar Shah, Juan Carlos Martinez-Gutierrez, Alejandro Ruiz ...

7. Sertraline (oral route) - Mayo Clinic

   Sertraline belongs to a group of medicines known as selective serotonin reuptake inhibitors (SSRIs). It works by increasing the activity of a chemical ...

8. Study of Radium-223 Dichloride Versus Placebo and Treatment With Exemestane / Everolimus in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast Cancer - Mayo Clinic

   Subjects must have experienced recurrent/progressive disease following treatment with a non-steroidal aromatase inhibitor (letrozole or anastrozole) in an ...

9. Publications - Eric Edwards, M.D. - Mayo Clinic

   Lu B, Shinohara ET, Edwards E, Geng L, Tan J, Hallahan DE. The use of tyrosine kinase inhibitors in modifying the response of tumor microvasculature to ...

10. Mayo Clinic researchers uncover new agents that eliminate cells associated with age-related diseases

    A recent study of human cell cultures shows that the drugs, fisetin and two BCL-XL inhibitors – A1331852 and A1155463 – cleared senescent cells in vitro.