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  1. Predicting Disease Progression in Pediatric Patients With Autosomal Dominant Polycystic Kidney Disease Using Urinary Crystal Burden as a Biomarker - Mayo Clinic

    About this study. The purpose of this study is to characterize urinary crystalluria, supersaturation, cytokines, and extracellular vehicles from activated ...

  2. Efficacy and Safety of Lubiprostone in Pediatric Subjects Aged ≥ 6 Years to < 18 Years With Functional Constipation - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. A Prospective Registry for Patients with REM Sleep Behavior Disorder and Polysomnographic REM Sleep without Atonia and Controls - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. IL-33 Production by Nasal Epithelial Cells - Clinical Trials

    About this study. This research study is being done for people who have asthma and chronic rhinosinusitis, hay fever, or you do not have any sinus disease, ...

  5. The Effects of Aortic Valve Replacement on Sleep Disordered Breathing, Heart Rate Variability and Ventricular Ectopy Burden in Patients with Severe Aortic Stenosis - Mayo Clinic

    Our overall goal is to determine whether the AVR improves SDB where present and sleep profiles (including sleepiness symptoms, quality of life and hypoxia).

  6. An Observational Study of Non-Invasive Respiratory Volume Monitoring After Extubation of Surgical and Neurological Patients Admitted to the Intensive Care Unit - Mayo Clinic

    An Observational Study of Non-Invasive Respiratory Volume Monitoring After Extubation of Surgical and Neurological Patients Admitted to the Intensive Care Unit.

  7. A Study of the Use of Quantiferon CMV Blood Test to Find the Length of CMV Prevention in CMV Donor (+) / Recipient (-) Solid Organ Transplant Recipients - Mayo Clinic

    The overall aim of this study is to evaluate the clinical utility of the QuantiFERON-CMV test in solid organ transplant recipients on CMV prophylaxis to predict ...

  8. Ph 3 Trial of Blinatumomab vs Investigator's Choice of Chemotherapy in Patients with Relapsed or Refractory ALL - Mayo Clinic

    This study seeks adult subjects with Relapsed/Refractory (R/R) B-precursor ALL. This is a phase 3 randomized, open label study designed to evaluate the efficacy ...

  9. Long-Term Safety of PF-00547659 in Ulcerative Colitis - Mayo Clinic

    Subjects with Ulcerative Colitis who have completed an induction study with PF-00547659 will receive an additional 72 weeks of open-label treatment to evaluate ...

  10. A Study to Evaluate the Effect of Medical Intervention on Sinonasal Inflammation in Patients with Chronic Sinusitis, Nasal Polyps and Positive Sinus Culture - Mayo Clinic

    About this study. The purpose of this study is to compare change in SNOT-22 score in patients who received medication therapy such as oral antibiotics, ...