Search Results 1231-1240 of 15737 for alt

  1. A Phase 1-2 Multi-Center Study Evaluating Axicabtagene Ciloleucel in Subjects With Refractory Aggressive Non-Hodgkin Lymphoma (ZUMA-1) - Mayo Clinic

    Serum alanine aminotransferase/aspartate aminotransferase (ALT/AST) ≤ 2.5 upper limit of normal (ULN);; Total bilirubin ≤ 1.5 mg/dl, except in subjects ...

  2. Ixazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib - Mayo Clinic

    Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 3 x. *Cockcroft-Gault Equation: Creatinine clearance for males = (140 - age)(actual ...

  3. A Study of SC-006 in Subjects With Advanced Cancer - Mayo Clinic

    Serum ALT and AST ≤× ULN (≤× ULN if evidence of hepatic involvement bymalignant disease);; Serum creatinine ≤.5× ULN or estimated filtration rate (eGFR) ...

  4. HEALEY ALS Platform Trial - Mayo Clinic

    Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) greater than 3 times the upper limit of normal (ULN);; eGFR < 30 mL/min/1.73m^2;; thyroid ...

  5. Safety Study of Chimeric Natriuretic Peptide(CD-NP) in Stable LVAD Patients - Mayo Clinic

    Elevated aspartate aminotransferase (AST) or alanine aminotransferase (ALT) at least 5 times the upper limit of normal or bilirubin at least 5 times the upper ...

  6. Safety and Efficacy of Simtuzumab (GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH) - Mayo Clinic

    Must have aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤ 10 x Central Laboratory Upper Limit of Normal (clULN); Must have serum ...

  7. Phase 1/2 Study of AG-221 in Subjects With Advanced Hematologic Malignancies With an IDH2 Mutation - Mayo Clinic

    Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) and Alkaline phosphatase (ALP) ≤3.0 × ULN (Upper limit of normal), unless considered due to ...

  8. A Study to Evaluate Mutanome-directed Immunotherapy in Patients with Squamous Cell Carcinoma of the Head and Neck - Mayo Clinic

    Serum transaminases: alanine aminotransferase [ALT] and aspartate aminotransferase [AST]) ≤ 2.5 x ULN;; Calculated creatinine clearance ≥ 40 mL/min using ...

  9. MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment - Mayo Clinic

    Adequate hepatic function as evidenced by: Normal serum total bilirubin; AST and ALT ≤ 2.5 x ULN (≤ 5 x ULN is acceptable if liver metastases are present) ...

  10. A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP) - Mayo Clinic

    Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) > 1.5 × upper limit of normal (ULN), confirmed by repeat testing;; Total bilirubin > 1.2 ...