Search Results 1231-1240 of 21997 for Inhibition
For subjects with Philadelphia-chromosome positive (Ph+) disease, failure or intolerance to a tyrosine kinase inhibitor therapy-containing regimen. ALL ...
Interferons, Everolimus (mTOR-inhibitors) or other systemic therapies within 4 weeks prior to enrollment. Known brain metastases, unless these metastases ...
Ongoing treatment with an ACE-inhibitor that is considered as the potential cause of a subject's cough or requiring treatment with an ACE-inhibitor during ...
Participation eligibility · Currently enrolled in an ongoing clinical study of LOXO-292 or another RET inhibitor. · Given the nature and objectives of this EAP, ...
inhibitors or inducers of CYP3A4. 5. Patients currently receiving acid-reducing agents and are unable to stop use at least 2 weeks prior to the first dose ...
For example, the overall response rate of immune checkpoint inhibitors (e.g., anti-PD1/PD-L1) is only 10% to 30%. Even in most initial responders, drug ...
Patients who are unwilling or unable to refrain from using hydroxymethylglutaryl coenzyme A (HMG CoA) reductase inhibitors (statins) starting 5 days before ...
Strong inhibitors of CYP1A2 (Cytochrome P450 family 1 subfamily A member 2) (example: fluvoxamine or enoxacin); Moderate inducers of CYP1A2 (limited to ...
* Prior participation in any rilzabrutinib studies or other BTK inhibitor studies. * History of treatment with an investigational drug within 6 months or 5 ...
... inhibitors or inducers and who are unwilling or unable to change to antiretroviral therapies without such interactions are ineligible because of the ...
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