Search Results 1151-1160 of 19926 for Receptor

  1. Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors - Mayo Clinic

    ... receptor positive (ER+/PR+, and Her2-) metastatic breast cancer, recurrent GBM, GASTRIC/GASTROESOPHAGEAL JUNCTION CANCER, advanced pancreatic adenocarcinoma ...

  2. Study Comparing CB-839 with Cabozantinib vs. Cabozantinib with Placebo in Patients with Metastatic Renal Cell Carcinoma - Mayo Clinic

    Small molecule receptor tyrosine kinase inhibitor (TKI) therapy (including investigational) within 2 weeks or 5 half-lives, whichever is longer;; Any type of ...

  3. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation - Mayo Clinic

    Treatment with endothelin receptor antagonists (ERAs), phosphodiesterase-5 (PDE5) inhibitors, intravenous (i.v)., subcutaneous (s.c.), or oral prostanoids ...

  4. Diabetes: How do I help protect my liver? - Mayo Clinic

    Alcohol: Does it affect blood pressure? Alpha blockers · Amputation and diabetes: How to protect your feet · Angiotensin II receptor blockers · Angiotensin- ...

  5. Clinical trials - Oncology (Medical)

    ... receptor positive, estrogen receptor-positive, human epidermal growth receptor-2 negative metastatic breast cancer after progression on previous endocrine ...

  6. Gary C. Sieck, Ph.D. - Mayo Clinic Faculty Profiles

    Sieck hypothesizes that brain-derived neurotrophic factor (BDNF) signaling through the high-affinity TrkB receptor is involved in motor neuron survival, and ...

  7. Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-52) - Mayo Clinic

    Prior therapy with an anti-PD-1, anti-PD-L1, or anti-PD-L2 agent, or with an agent directed to another co-inhibitory T-cell receptor; Known human ...

  8. Mayo Clinic Q&A podcast: Cancer Center patient navigators

    ... receptor-T cell therapy. Related Articles. Mayo Clinic Q&A: Why are younger people being diagnosed with colorectal cancer? featured image. Cancer. Mayo Clinic ...

  9. A Study to Evaluate PDS0101 and Pembrolizumab Combination to Treat Subjects with HPV16 + Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma - Mayo Clinic

    an agent directed to another stimulatory or co-inhibitory T-cell receptor (e.g.. CTLA-4, OX40, CD137) and was discontinued from that treatment due to a Grade ...

  10. Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients with Early-Stage Breast Cancer that was Removed by Surgery - Mayo Clinic

    Non-hormone-sensitive breast cancer (estrogen and progesterone receptor negative (ER- and PR-) or; Grade III histology or; Oncotype recurrence score > 25 or.