Search Results 101-110 of 37957 for Two-phase

  1. Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies - Mayo Clinic

    - To assess the pharmacodynamics (PD), immune response, and preliminary disease response. Phase 2 (stage 1): to evaluate the following objectives for Isatuximab ...

  2. Phase 2 Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of DCR-PHXC Solution for Injection (subcutaneous use) in Patients with Primary Hyperoxaluria - PHYOX 2 - Mayo Clinic

    Phase 2 Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of DCR-PHXC Solution for Injection (subcutaneous ...

  3. Lymphedema: Diagnosis and treatment - Mayo Clinic

    Stage 2 (irreversible lymphedema): Fibrosis — the deposition of loose, disorganized collagen tissue — has occurred. Without intervention, no matter how long the ...

  4. Phase 1-2 Study of ADXS11-001 or MEDI4736 Alone or Combo In Cervical or HPV+ Head & Neck Cancer - Mayo Clinic

    Part A: (ADXS11-001 + MEDI4736 Combination Therapy) will determine the safety and tolerability of the combination and to identify a RP2D. Part B: Phase 2 design ...

  5. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer - Mayo Clinic

    This study consists of two phases: Dose Escalation (Phase 1b) and Dose Expansion (Phase 2) The Dose Escalation phase will evaluate the safety and ...

  6. South Beach Diet - Mayo Clinic

    Phase 1. This two-week phase aims to jump-start your weight loss. You cut out almost all carbs from your diet. · Phase 2. This phase aims to help you lose weight ...

  7. Clinical trials - Oncology (Medical)

    ... phase 2 dose (RP2D) and preferred schedule, and assess preliminary anti ... The study will be performed in two phases: Phase I will be performed for ...

  8. Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 - Mayo Clinic

    The Phase 2 portion of this study evaluates the efficacy and safety of MRTX849 monotherapy and in combination with pembrolizumab in cohorts of patients with ...

  9. Type 2 diabetes - Symptoms and causes - Mayo Clinic

    End-stage kidney disease may need to be treated with mechanical filtering of the kidneys, called dialysis, or a kidney transplant. Eye damage. Diabetes ...

  10. Clinical trials - Oncology (Medical)

    The study will be performed in two phases: Phase I will be performed for biologic validation of marker candidates from a discovery cohort and phase II will ...